21 Results for "

Type-II-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (21)

21 Results for "Type-II-IN-1" in MCE Product Catalog:

Type-II-IN-1
Type-II-IN-1
0 Images
Cat. No.: HY-18911
CAS No.: 1419299-81-2
Target:  

Syk

Research Areas:  

Inflammation/Immunology

Type-II-IN-1 (Compound 3) is a type II spleen tyrosine kinase (Syk) inhibitor with an IC50 of 2.1 nM. Type-II-IN-1 can bind to the DFG-out conformation of Syk. Type-II-IN-1 can be used for the research of immunology, such as asthma [1].
loading...
    loading...
View All Sizes
4
Phytosphingosine
Phytosphingosine
0 Images
4 Cited Publications
Cat. No.: HY-W011303
CAS No.: 554-62-1
Synonyms: 4-HydroxysphINganINe
Category:  

Infection Human Gut Microbiota Metabolites Natural Products Metabolic Disease Endogenous metabolite Disease Research Fields Cancer

Target:  

Apoptosis Endogenous Metabolite Fungal Free Fatty Acid Receptor

Phytosphingosine is a phospholipid with anti-inflammatory, antibacterial, and anti-cancer activities, which can induce apoptosis. Phytosphingosine is an immune regulator and can be used in the study of inflammatory skin diseases. Phytosphingosine is also an activator of GPR120 with an IC50 value of 33.4 μM and can be used in the study of type II diabetes .
loading...
    loading...
View All Sizes
3
Cytochrome C
Cytochrome C
0 Images
3 Cited Publications
Cat. No.: HY-125857
CAS No.: 9007-43-6
Purity:  99.9%
Cytochrome C is a multi-functional enzyme involving in life and death decisions of the cell. Cytochrome C is essential in mitochondrial electron transport and intrinsic type II apoptosis .
loading...
    loading...
View All Sizes
1
Methyl pyruvate
Methyl pyruvate
0 Images
1 Cited Publications
Cat. No.: HY-W012985
CAS No.: 600-22-6
Target:  

ATP Synthase Apoptosis

Research Areas:  

Neurological Disease Metabolic Disease Cancer

Methyl pyruvate is a p53/p21 axis inhibitor, intrinsic apoptosis inhibitor, cytotoxic agent, ATP production enhancer, proteasome function restorer, TDP-43 localization normalizer, ATP-sensitive potassium (K +ATP) channel inhibitor, depolarizer, and insulin secretagogue [1] .Methyl pyruvate turns off apoptotic pathways, induces cancer cell death, acts as a substrate for dimeric dihydrodiol dehydrogenase, enhances TCA cycle activity, rescues proteasome impairment and TDP-43 mislocalization, inhibits K +ATP channels independent of ATP, depolarizes pancreatic β-cell membranes, modulates insulin secretion, and enters pancreatic β-cell mitochondria via a specific transporter [1] .Methyl pyruvate can be used for the research of lung adenocarcinoma, ovarian clear cell adenocarcinoma, breast adenocarcinoma, amyotrophic lateral sclerosis, and type II diabetes .
loading...
    loading...
View All Sizes
Masoprocol
Masoprocol
0 Images
Cat. No.: HY-109500
CAS No.: 27686-84-6
Purity:  99.76%
Synonyms: meso-Nordihydroguaiaretic acid; meso-NDGA
Category:  

Metabolic Disease Phenols Polyphenols Plants Other Families Extract Disease Research Fields

Target:  

Lipoxygenase

Masoprocol (meso-Nordihydroguaiaretic acid) is a potent and orally active lipoxygenase inhibitor. Masoprocol shows antihyperglycemic activity. Masoprocol decreases the glucose concentration and hepatic triglyceride in vivo. Masoprocol has the potential for the research of type II diabetes .
loading...
    loading...
View All Sizes
AM-5262
AM-5262
0 Images
Cat. No.: HY-16619
CAS No.: 1222088-90-5
Target:  

Free Fatty Acid Receptor

Research Areas:  

Metabolic Disease

AM-5262 is a GPR40 full agonist with an EC50 value of 0.081 μM. AM-5262 can be used for the research of type II diabetes .
loading...
    loading...
View All Sizes
Aleglitazar
Aleglitazar
0 Images
Cat. No.: HY-14728
CAS No.: 475479-34-6
Purity:  99.74%
Synonyms: R1439; RO0728804
Target:  

PPAR

Research Areas:  

Metabolic Disease

Aleglitazar (R1439) is a potent dual PPARα/γ agonist, with IC50s of 38 nM and 19 nM for human PPARa and PPARγ, respectively. Aleglitazar can be used for the research of type II diabetes .
loading...
    loading...
View All Sizes
LH-RH (4-10)
LH-RH (4-10)
0 Images
Cat. No.: HY-P3675
CAS No.: 51776-33-1
Target:  

GnRH Receptor

Research Areas:  

Endocrinology

LH-RH (4-10) is a heptapeptide, one of major degradation products of luteinising-hormone releasing hormone (LHRH) via pituitary and hypothalamus. LH-RH (4-10) produced in macrophages and type II pneumocytes .
loading...
    loading...
View All Sizes
Oxeglitazar
Oxeglitazar
0 Images
Cat. No.: HY-114632
CAS No.: 280585-34-4
Target:  

PPAR

Research Areas:  

Metabolic Disease

Oxeglitazar is an orally active compound that can be used for the research of type II diabetes .
loading...
    loading...
View All Sizes
MK-8666 tromethamine
MK-8666 tromethamine
0 Images
Cat. No.: HY-141653
CAS No.: 2056254-98-7
Target:  

Free Fatty Acid Receptor

Research Areas:  

Metabolic Disease

MK-8666 (tromethamine) is a GPR40 agonist. MK-8666 (tromethamine) can be used in the research of type II diabetes .
loading...
    loading...
View All Sizes
Thiazinamium chloride
Thiazinamium chloride
0 Images
Cat. No.: HY-U00267
CAS No.: 4320-13-2
Target:  

Cholinesterase (ChE)

Research Areas:  

Inflammation/Immunology

Thiazinamium (chloride) possesses potent anticholinergic and antiallergic activity and inhibits TxB2 synthesis with IC50 value of 0.2 µM. Thiazinamium (chloride) is structurally similar to H-1 antagonists Promethazine (HY-B1296). Thiazinamium (chloride) stimulates the phosphatidylcholine secretion in adult rat type II pneumocytes .
loading...
    loading...
View All Sizes
AMG-222 tosylate
AMG-222 tosylate
0 Images
Cat. No.: HY-19859
CAS No.: 1163719-08-1
Target:  

Dipeptidyl Peptidase

Research Areas:  

Metabolic Disease

AMG-222 (tosylate) is a DPP-IV inhibitor that can be used in the research of type II diabete .
loading...
    loading...
View All Sizes
AMPK activator 14
AMPK activator 14
0 Images
Cat. No.: HY-162042
CAS No.: 1356632-18-2
Target:  

AMPK

Research Areas:  

Metabolic Disease

AMPK activator 14 (compound 32) is an orally active AMPK activator. AMPK activator 14 decreases fasted glucose and insulin levels in a db/db mouse model of Type II diabetes .
loading...
    loading...
View All Sizes
Cangorinine E-1
Cangorinine E-1
0 Images
Cat. No.: HY-N12191
CAS No.: 155944-24-4
Category:  

Alkaloids Celastraceae Extract Other Alkaloids Terpenoids Sesquiterpenes Plants 500 - Internal Server Error | MedChemExpress

Oops!

Sorry, Something went wrong on our server.
Our team has been notified and is working to fix the issue.