31 Results for "

acetoxymethyl ester

" in MedChemExpress (MCE) Product Catalog:
Products (31)

31 Results for "acetoxymethyl ester" in MCE Product Catalog:

93
93 Publications Verification
Cat. No.: HY-D0041
CAS No.: 148504-34-1
Synonyms: Calcein acetoxymethyl ester
Calcein AM, has cell membrane permeability and can easily enter the cell. Calcein AM has no fluorescence and is hydrolyzed by endogenous esterase in the cell to produce polar molecule Calcein (Calcein), which has strong negative charge and cannot permeate the cell membrane. Calcein can emit strong green fluorescence, so it is often used with Propidium Iodide for cell viability/virulence detection, excitation/emission wavelength: 494/515 nm .
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11
11 Cited Publications
Cat. No.: HY-D0973
CAS No.: 99590-86-0
Synonyms: EGTA acetoxymethyl ester
EGTA-AM is a membrane permeable form of EGTA, can be passively loaded into cells to generate intracellular EGTA; EGTA-AM is also a Ca 2+ chelator with slow chelating dynamics.
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11
11 Cited Publications
Cat. No.: HY-101883A
BCECF Acetoxymethyl ester is a cell membrane permeable compound widely-used as a fluorescent indicator for intracellular pH. BCECF Acetoxymethyl ester could diffuse through the cell membrane and intracellular esterase cleave the ester bond releasing BCECF (HY-101882). BCECF allows measurements in the physiological pH range 6.0-8.0. Excitation ratio: 490/440 nm; Emission intensity: 535 nm .
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9
9 Cited Publications
Cat. No.: HY-101897
CAS No.: 108964-32-5
Purity:  99%
Synonyms: Fura-2 acetoxymethyl ester
Fura-2 AM is a membrane permeable, intracellular, UV light-excitable and ratiometric fluorescent Ca 2+ (calcium ion) indicator. Fura-2 AM crosses cell membranes and is converted to Fura-2 (HY-D0110A) via cellular esterases. Fura-2 AM can be used to detect calcium in cells.
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2
2 Cited Publications
Cat. No.: HY-134124
CAS No.: 92614-59-0
Purity:  95.8%
Research Areas:  

Metabolic Disease

Glutathione ethyl ester is a cell-permeable GSH donor and provides an efficient supply of GSH to the oocyte. Glutathione ethyl ester shows positive effect on the in vitro production of embryos by enhancement of the antioxidative defense .
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2
2 Cited Publications
Cat. No.: HY-141894
CAS No.: 2990123-10-7
Purity:  99.04%
Research Areas:  

Metabolic Disease

5-Ph-IAA-AM is an eggshell-permeable 5-Ph-IAA (HY-134653) analog which contains an acetoxymethyl (AM) group. 5-Ph-IAA-AM affords an enhanced protein degradation in laid embryos. 5-Ph-IAA-AM can be used to disclosure the roles of proteins in C. elegans, in particular those that are involved in embryogenesis and development, through temporally controlled protein degradation .
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2
2 Cited Publications
Cat. No.: HY-D1746
CAS No.: 162303-59-5
Synonyms: EDTA acetoxymethyl ester; Ethylenediaminetetraacetic acid acetoxymethyl ester
EDTA-AM (ethylenediaminetetraacetic acid, acetoxymethyl ester) is the membrane-permeant form of the metal chelator EDTA (HY-Y0682). Live cells passively load EDTA-AM by incubating with EDTA-AM. Once internalized, cytoplasmic esterase decomposes AM esters, releasing the active ligand EDTA, which isolates metal ions within the cell. EDTA-AM induces an arrest of mitotic progression and chromosome decondensation .
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1
1 Cited Publications
Cat. No.: HY-101898
CAS No.: 112926-02-0
Purity:  96%
Synonyms: Indo-1 acetoxymethyl ester
Calcium is an important part of the human body, usually in the form of calcium, a large number of bones and teeth of the human body, a small amount of blood and tissues. MCE calcium ion detection probe can specifically identify intracellular calcium ions, with high sensitivity, low cytotoxicity, increased AM acetylmethyl ester can enter the cell well, after being sheared by the intracellular esterase stay in the cell to bind to calcium ions, produce strong fluorescence, in addition, Mag-indo-1/AM and Mag-Fluo-4 AM at a certain concentration (usually 5 mM) can effectively identify intracellular magnesium ions .
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1
1 Cited Publications
Cat. No.: HY-124298
CAS No.: 168482-84-6
Purity:  99.00%
Target:  

Fluorescent Dye

Research Areas:  

Others

Calcein Blue AM is a cell staining agent. Calcein Blue AM serves as a substrate for intracellular esterases, which hydrolyze its acetoxymethyl (AM) ester group to convert the non-fluorescent reagent into fluorescent Calcein Blue. Calcein Blue AM passively penetrates the plasma membrane of both live and dead cells; it is converted into a polar fluorescent product and retained in the cytoplasm of live cells, whereas dead cells cannot retain the dye. Calcein Blue AM exhibits significant dye leakage, and its fluorescence intensity gradually decreases over time. Calcein Blue AM can be used for endpoint-based cell viability assays and short-term cell tracking experiments with a duration of no more than 4 hours.
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Cat. No.: HY-D1093
CAS No.: 126208-13-7
Target:  

Fluorescent Dye

Research Areas:  

Others

Carboxy SNARF-1, acetoxymethyl ester (5/6-mixture) is a fluorescent probe used for intracellular pH measurement. The detection wavelengths of Carboxy SNARF, acetoxymethyl ester are Ex/Em = 540/590 nm and 540/650 nm, with an excitation wavelength of 540 nm. Emission signals at 590 nm and 650 nm are recorded simultaneously, and the ratio of these emission signals yields a linear measurement of intracellular pH .
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Cat. No.: HY-158741
CAS No.: 1369302-24-8
Synonyms: APG-2 acetoxymethyl ester
IPG-2 AM (APG-2 Acetoxymethyl ester) is a membrane-permeant acetoxymethyl ester derivative and selective fluorescent potassium ion indicator. IPG-2 AM exhibits fluorescence increases proportional to extracellular potassium ion concentrations. IPG-2 AM enables real-time monitoring of cytosolic free potassium ion fluxes in human platelets and macrophages. IPG-2 AM can be used for the research of intracellular potassium concentration dynamics .
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Cat. No.: HY-44323
CAS No.: 13639-50-4
Synonyms: (2R,3R,4S,5R,6S)-2-(acetoxymethyl)-6-(acetylthio)tetrahydro-2H-pyran-3,4,5-triyl triacetate
Target:  

Drug Intermediate

Research Areas:  

Others

2,3,4,6-Tetra-O-acetyl-1-S-acetyl-1-thiohexopyranose ((2R,3R,4S,5R,6S)-2-(Acetoxymethyl)-6-(acetylthio)tetrahydro-2H-pyran-3,4,5-triyl triacetate) is a drug intermediate for synthesis of various active compounds.
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Cat. No.: HY-I0838R
CAS No.: 915095-99-7
Target:  

Reference Standards

(2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate (Standard) is the analytical standard of (2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate. This product is intended for research and analytical applications.
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Cat. No.: HY-176287
ARN25657 is a dual-acting D3R/GSK-3β modulator. ARN25657 has both partial D3R agonist activity (EC50 = 15.2 nM, Ki =1.5 nM) and potent GSK-3β inhibitor activity (IC50 = 19.3 nM). ARN25657 exhibits excellent GSK-3β selectivity over FYN, PKA, and CDK5/p35. ARN25657 inhibits P-glycoprotein (P-gP)-mediated acetoxymethyl calcein efflux and improves in vitro ADME properties while maintaining a balanced dual-target profile. ARN25657 is useful for studying bipolar disorder and related neuropsychiatric disorders .
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Cat. No.: HY-W010321
CAS No.: 623-17-6
Target:  

Drug Intermediate

Research Areas:  

Others

Furfuryl acetate can be used in the synthesis of 5-acetoxymethyl-2-vinylfuran and 5-hydroxymethyl-2-vinylfuran .
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Cat. No.: HY-134271
CAS No.: 272445-71-3
Target:  

Drug Derivative PKG

Research Areas:  

Cancer

8-Br-cGMP-AM is a cGMP analog. 8-Br-cGMP-AM is a membrane-permeable, bioactivatable acetoxymethyl ester designed to avoid rapid cGMP turnover. 8-Br-cGMP-AM mediates the phosphorylation of CRP4. 8-Br-cGMP-AM has anticancer activity against leukemia. 8-Br-cGMP-AM can be used for research on acute myeloid leukemia .
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Cat. No.: HY-N3073
CAS No.: 20045-06-1
Synonyms: Picraline, 16-de(acetoxymethyl)-16-formyl-
Picralinal (Picraline, 16-de(acetoxymethyl)-16-formyl-) is a Triterpenoids product that can be isolated from the whole plants of Scilla scilloides. .
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Cat. No.: HY-158746
CAS No.: 1070771-36-6
Synonyms: Fluo-2 acetoxymethyl ester; Fluo-2 ha; Fluo-2 high affinity
Fluo-2 AM (Fluo-2 acetoxymethyl ester) is a fluorescent dye, that can be used for detection of intracellular calcium ion concentration .
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Cat. No.: HY-W555447
CAS No.: 55692-87-0
Research Areas:  

Others

(2R,3S,4S,5R,6S)-2-(Acetoxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triyl triacetate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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Cat. No.: HY-W010321R
CAS No.: 623-17-6
Research Areas:  

Others

Furfuryl acetate (Standard) is the analytical standard of Furfuryl acetate (HY-W010321). This product is intended for research and analytical applications. Furfuryl acetate can be used in the synthesis of 5-acetoxymethyl-2-vinylfuran and 5-hydroxymethyl-2-vinylfuran .
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