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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2889 Results for "
aci-nitro intermediates
" in MedChemExpress (MCE) Product Catalog:
Products (2889)
2889 Results for "aci-nitro intermediates" in MCE Product Catalog:
38
38 Publications Verification
Synonyms: β-Nicotinamide mononucleotide; β-NM; NMN
Category:
Neurological Disease Other disease Anti-aging Endogenous metabolite Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Disease markers Microorganism Disease Research Fields Cancer
Target:
32
32 Cited Publications
Target:
Research Areas:
TRAM-34 is a highly selective blocker of intermediate-conductance calcium-activated K + channel (IKCa1) (Kd=20 nM).
26
24
Category:
Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Other Diseases Microorganism Endogenous metabolite Disease Research Fields
Target:
24
Target:
Research Areas:
Protoporphyrin IX disodium is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX disodium also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX disodium is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX disodium causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX disodium is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .
20
20
Category:
Human Gut Microbiota Metabolites Disease markers Metabolic Disease Amino acids Nervous System Disorder Microorganism Endogenous metabolite Disease Research Fields
Target:
13
13 Cited Publications
Research Areas:
IMT1 is a first-in-class specific and noncompetitive human mitochondrial RNA polymerase (POLRMT) inhibitor. IMT1 causes a conformational change of POLRMT, which blocks substrate binding and transcription in a dose-dependent way in vitro. IMT1 reduces deoxynucleoside triphosphate levels and citric acid cycle intermediates, resulting in a marked depletion of cellular amino acid levels. IMT1 has the potential for mitochondrial transcription disorders related diseases .
12
12
12 Cited Publications
Cat. No.: HY-W015410
CAS No.: 150-90-3
Target:
12
12 Cited Publications
Synonyms: 6PPD-Quinone
Category:
Alkaloids Quinones Other Alkaloids Other Diseases Benzene Quinones Endogenous metabolite Disease Research Fields
Target:
9
9 Cited Publications
Cat. No.: HY-W017389
CAS No.: 69-89-6
8
8 Cited Publications
Cat. No.: HY-W010347
CAS No.: 6027-13-0
Category:
Human Gut Microbiota Metabolites Anti-aging Ketones, Aldehydes, Acids Microorganism Endogenous metabolite Disease Research Fields Inflammation/Immunology
Target:
8
8 Cited Publications
Cat. No.: HY-N3007
CAS No.: 73692-50-9
Category:
Other Families Extract Endogenous metabolite Human Gut Microbiota Metabolites Plant Flavonoids Chalcones Phenols Polyphenols Disease Research Fields Inflammation/Immunology
Target:
8
8 Cited Publications
Synonyms: Acetyl-CoA trisodium
8
8 Cited Publications
Synonyms: Acetyl-CoA lithium
7
7 Cited Publications
Cat. No.: HY-W013636
CAS No.: 328-50-7
Synonyms: Alpha-Ketoglutaric acid; 2-Oxoglutaric acid
Category:
Anti-aging Endocrine diseases Endogenous metabolite Immune System Disorder Ketones, Aldehydes, Acids Other Diseases Disease markers Nervous System Disorder Microorganism Disease Research Fields
Target:
7
Target:
Research Areas:
Madrasin (DDD00107587) is a splicing inhibitor that prevents formation of both splicing intermediates and products in vitro and interferes with one or more early steps in the pathway of spliceosome assembly. Madrasin also can inhibit pre-mRNA splicing in vitro and modify splicing of endogenous pre-mRNA in cells .
7
7 Cited Publications
Cat. No.: HY-W013636A
CAS No.: 22202-68-2
Synonyms: Alpha-Ketoglutaric acid Sodium
Target:
7
7 Cited Publications
Cat. No.: HY-W013636B
CAS No.: 71686-01-6
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
