Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
alkaline properties
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "alkaline properties" in MCE Product Catalog:
4
Target:
Research Areas:
Toluidine Blue (Toluidine Blue O) is an alkaline quinonimine dye (vivo dye) with high affinity for acidic tissue components, staining nuclei blue and polysaccharides purple. Toluidine Blue shows heterostaining properties for mast cells, mucins and chondrocytes. Toluidine Blue can stain different components of plant tissues and cells in different colours. Toluidine Blue is also used as a diagnostic aid to identify malignant lesions, such as cancer .
4
1
Research Areas:
Domiphen bromide is a cationic active quaternary ammonium salt and also an inhibitor of HERG channels (IC50: 9 nM), aminopeptidase-like enzymes, Escherichia coli alkaline phosphatase, and α-chymotrypsin. Domiphen bromide has multiple activities such as antibacterial, antimalarial, and disinfectant properties, and it is also a synergist of Colistin (HY-113678). Domiphen bromide can be used as a chemical preservative and a cationic surfactant, and it can also be used in the research of bacterial infectious diseases such as pharyngitis, thrush, and oral ulcers .
1
1 Cited Publications
Cat. No.: HY-169703
CAS No.: 1251839-15-2
Target:
Research Areas:
SPA0355 is a thiourea derivative that has antioxidant and anti-inflammatory properties. SPA0355 inhibits the RANKL (receptor activator of nuclear factor κB ligand) induced osteoclast formation in primary bone marrow-derived macrophages. SPA0355 also suppresses the activation of the MAPKs, Akt, and NF-κB pathways. Additionally, SPA0355 promotes osteoblast differentiation, increases alkaline phosphatase activity, and enhances mineral nodule formation. SPA0355 can protect ovariectomized mice from bone loss by stimulating osteoblast differentiation and inhibiting osteoclast resorption, making it useful for studying postmenopausal osteoporosis .
Cat. No.: HY-W923198
CAS No.: 480439-15-4
Synonyms: Methacryloyloxy fluorescein
Category:
Triterpenes Metabolic Disease Other Families Extract Biological Pesticide Research Agricultural Research Infection Plant Terpenoids Disease Research Fields Inflammation/Immunology
Target:
Cat. No.: HY-P11087
CAS No.: 134335-45-8
Research Areas:
Cat. No.: HY-B2203
CAS No.: 27214-00-2
Target:
Research Areas:
Monocalcium glycerophosphate is an inhibitor of intestinal alkaline phosphatase F3, and it has anti-cavity properties. Monocalcium glycerophosphate is a source of calcium and phosphorus in total parenteral nutrition solutions, helps prevent the mineralization and development of bones from intravenous nutrition, and maintains the integrity of the intestinal epithelium .
Target:
Research Areas:
Naphthol AS-TR Phosphate disodium is a water-soluble dye commonly used as an enzymatic substrate in various biochemical assays to detect alkaline phosphatase activity. Naphthol AS-TR Phosphate disodium has unique chemical properties that allow it to be hydrolyzed by alkaline phosphatase, forming a colored product that can be detected spectrophotometrically. This makes it a useful tool for monitoring enzyme activity in biological samples such as serum or urine.
Research Areas:
3-Carboxy-7-Hydroxycoumarin is a 7-hydroxycoumarin (umbelliferone) fluorescent dye and antibody-conjugated labeling agent with UV excitation properties. 3-Carboxy-7-Hydroxycoumarin undergoes deprotonation in neutral-to-alkaline environments, producing strong blue fluorescence. The absorption/emission maxima of 3-Carboxy-7-Hydroxycoumarin are 386/448 nm. 3-Carboxy-7-Hydroxycoumarin is applicable for related research such as fluorescent probe synthesis and covalent protein labeling .
Cat. No.: HY-167657
CAS No.: 56488-58-5
Target:
Research Areas:
Tizolemide is a sulphonamide diuretic compound that has alkaline properties and is cleared by a tubular transport system. Tizolemide induces changes of passive transport components across the basolateral membrane of isolated frog skin .
Cat. No.: HY-116022B
CAS No.: 68189-42-4
Synonyms: p-Nitrophenyl phosphate ditromethamine
Research Areas:
Domiphen bromide (Standard) is the analytical standard of Domiphen bromide (HY-B1467). This product is intended for research and analytical applications. Domiphen bromide is a cationic active quaternary ammonium salt and also an inhibitor of HERG channels (IC50: 9 nM), aminopeptidase-like enzymes, Escherichia coli alkaline phosphatase, and α-chymotrypsin. Domiphen bromide has multiple activities such as antibacterial, antimalarial, and disinfectant properties, and it is also a synergist of Colistin (HY-113678). Domiphen bromide can be used as a chemical preservative and a cationic surfactant, and it can also be used in the research of bacterial infectious diseases such as pharyngitis, thrush, and oral ulcers.
Cat. No.: HY-184612
Mesoporous polydopamine nanoparticles are mesoporous nanomaterials formed by the self-polymerization of dopamine hydrochloride under alkaline conditions. Their main component is the dopamine polymer, a biomacromolecule exhibiting good adhesion and reducing properties, demonstrating excellent biocompatibility and bio-interaction capabilities.
Cat. No.: HY-184614
Mesoporous polydopamine nanoparticles are mesoporous nanomaterials formed by the self-polymerization of dopamine hydrochloride under alkaline conditions. Their main component is the dopamine polymer, a biomacromolecule exhibiting good adhesion and reducing properties, demonstrating excellent biocompatibility and bio-interaction capabilities.
Cat. No.: HY-D3164
CAS No.: 1380316-56-2
Target:
Research Areas:
TPE-Cy is a fluorescent probe with both aggregation-induced emission (AIE) property and pH-dependent luminescent behavior. TPE-Cy exhibits significant luminescent differences under different acidic and alkaline conditions: it shows moderate to strong red emission with linear variation with pH in acidic environments and within the pH range of 5-7, weak or even no emission within the pH range of 7-10, and switches to blue emission under alkaline conditions. TPE-Cy possesses excellent cell permeability and biocompatibility, enabling accurate ratiometric pH sensing and imaging monitoring in living cells via confocal microscopy, ratiometric analysis and flow cytometry .
Cat. No.: HY-D3131
CAS No.: 2243068-74-6
Target:
Research Areas:
Lyso-MPCB is a two-photon fluorescent probe used for lysosomal pH detection and autophagy monitoring. Lyso-MPCB integrates a benzimidazole pH-responsive group and a morpholine lysosome-targeting group, enabling specific localization to lysosomes. The fluorescence properties of Lyso-MPCB change with protonation, exhibiting blue fluorescence under alkaline conditions and green fluorescence under acidic conditions .
Cat. No.: HY-179379
Target:
Research Areas:
EP4 receptor agonist 3 prodrug (Compound 9) is a prodrug of EP4 receptor agonist (Compound 1a). EP4 receptor agonist 3 prodrug itself has no agonistic activity on the EP4 receptor and needs to be specifically hydrolyzed by intestinal alkaline phosphatase (IAP) in the intestine to release the active molecule, which then exerts the EP4 receptor agonistic effect locally in the intestine. EP4 receptor agonist 3 prodrug has colonic targeting properties and significantly alleviates colitis in mice .
Cat. No.: HY-DY2019
Target:
Research Areas:
Toluidine Blue Staining Solution (1%, Phosphate Buffer) is an alkaline quinonimine dye (vivo dye) with high affinity for acidic tissue components, staining nuclei blue and polysaccharides purple. Toluidine Blue Staining Solution (1%, Phosphate Buffer) shows heterostaining properties for mast cells, mucins and chondrocytes. Toluidine Blue Staining Solution (1%, Phosphate Buffer) can stain different components of plant tissues and cells in different colours. Toluidine Blue Staining Solution (1%, Phosphate Buffer) is also used as a diagnostic aid to identify malignant lesions, such as cancer .
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
