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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1037 Results for "
anticancer compound
" in MedChemExpress (MCE) Product Catalog:
Products (1037)
1037 Results for "anticancer compound" in MCE Product Catalog:
99
99 Publications Verification
Synonyms: Luteoline; Luteolol; Digitoflavone
46
46 Cited Publications
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Research Areas:
BRM/BRG1 ATP Inhibitor-1 (compound 14) is an orally active allosteric dual brahma homolog (BRM)/SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily A member 2 (SMARCA2) and brahma related gene 1 (BRG1)/SMARCA4 ATPase activity inhibitor, both IC50s are below 0.005 µM. BRM/BRG1 ATP Inhibitor-1 has anticancer activity .
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43
Category:
Endogenous metabolite Polygonaceae Extract Quinones Human Gut Microbiota Metabolites Plant Anthraquinones Phenols Polyphenols Rheum palmatum L. Extract Microorganism Disease Research Fields Cancer
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29
29 Cited Publications
Synonyms: SPI-1005; PZ-51; CCG-39161
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Research Areas:
Infection Neurological Disease Inflammation/Immunology Cancer
Ebselen (SPI-1005), a glutathione peroxidase mimetic, is a potent voltage-dependent calcium channel (VDCC) blocker . Ebselen potently inhibits M pro (IC50=0.67 μM) and COVID-19 virus (EC50=4.67 μM) .Ebselen is an inhibitor of HIV-1 capsid CTD dimerization. Ebselen, an organoselenium compound, can permeate the blood-brain barrier and has anti-inflammatory, antioxidant and anticancer activity .
21
21 Cited Publications
Synonyms: Baicalein 6-methyl ether; 6-Methoxybaicalein
19
19 Cited Publications
Synonyms: Rheic Acid; Rhubarb yellow; Monorhein
17
17 Cited Publications
Synonyms: (S)-(+)-[6]Gingerol
15
15 Cited Publications
Synonyms: Luteolin 7-glucoside; Luteolin 7-O-β-D-glucoside
14
14 Cited Publications
Synonyms: [6]-Shogaol; 6-Shogaol
Category:
Plant Monophenols Zingiberaceae Extract Phenols Zingiber officinale Roscoe Extract Disease Research Fields Cancer
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14
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CBL0137, a curaxin compound, is a histone chaperone facilitates chromatin transcription (FACT) inhibitor. CBL0137 downregulates NF-κB and activates p53. CBL0137 restores both histone H3 acetylation and trimethylation. CBL0137 is an anticancer agent. CBL0137 induces cancer cell apoptosis .
13
13 Cited Publications
BI-3406 (compound I-6) is an orally active, highly potent and selective inhibitor of the interaction between KRAS and Son of Sevenless 1 (SOS1) with an IC50 of 6 nM. BI-3406 potently reduces the formation of GTP-loaded KRAS, and inhibits MAPK pathway signaling. BI-3406 has anticancer activity .
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8 Cited Publications
STL127705 (Compound L) is a potent Ku 70/80 heterodimer protein inhibitor with an IC50 of 3.5 μM. STL127705 interferes the binding of Ku70/80 to DNA and by inhibits the activation of the DNA-PKCS kinase. STL127705 shows antiproliferative and anticancer activity. STL127705 induces apoptosis .
7
7 Cited Publications
Synonyms: Eleutheroside A; β-Sitosterol β-D-glucoside
6
6 Cited Publications
WDR5-IN-4 TFA (Compound C6) is an inhibitor of the WIN site of chromatin-associated WD repeat-containing protein 5 (WDR5), with a Kd of 0.1 nM. WDR5-IN-4 TFA displaces WDR5 from chromatin and decreases the expression of associated genes, causing translational inhibition, nucleolar stress. Anti-cancer activity .
6
6 Cited Publications
WDR5-IN-4 (Compound C6) is a WIN site inhibitor of chromatin-associated WD repeat domain 5 protein (WDR5), Kd The value is 0.1 nM. WDR5-IN-4 is able to displace WDR5 from chromatin and reduce the expression of related genes, causing translation inhibition and nucleolar stress. Has anti-cancer effects .
5
5 Cited Publications
Cat. No.: HY-N4187
CAS No.: 144506-15-0
5
5
5 Cited Publications
Cat. No.: HY-N0498
CAS No.: 13063-04-2
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
