27 Results for "

beta-defensin

" in MedChemExpress (MCE) Product Catalog:
Products (27)

27 Results for "beta-defensin" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-N7057
CAS No.: 112-05-0
Synonyms: Pelargonic acid
Nonanoic acid (Pelargonic acid) is a naturally-occurring saturated fatty acid with nine carbon atoms. Nonanoic acid significantly reduces bacterial translocation, enhances antibacterial activity, and remarkably increases the secretion of porcine β-defensins 1 (pBD-1) and pBD-2 .
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1
1 Cited Publications
Cat. No.: HY-P7135
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: defensin beta 4A; beta-defensin 2; BD-2; hBD-2; defensin; beta 2; Skin-antimicrobial peptide 1; SAP1; DEFB4A; DEFB102; DEFB2; DEFB4; DEFB4B
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P2315
CAS No.: 452274-53-2
Synonyms: HβD-1
Research Areas:  

Infection Cancer

Human β-defensin-1 (HβD-1) is an antimicrobial peptide and immunomodulator that induces angiogenin secretion from fibroblasts through EGFR, JNK, NF-κB, Src, and p38 signaling pathways, and binds CCR6 to activate G protein signaling, while also inducing ER stress, apoptosis, cell cycle arrest, and autophagy. Human β-defensin-1 can be used in research on hepatocellular carcinoma, influenza A virus infection, male infertility, colon cancer, and bacterial infections caused by antibiotic-resistant strains .
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Cat. No.: HY-P5189A
Research Areas:  

Others

His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA, is a growth hormone releasing peptide, as well as a metabolite of GHRP-1. GHRP-1, or Ala-His-D-beta Nal-Ala-Trp-D-Phe-Lys-NH2, has the effect of promoting the release of growth hormone (GH). GHRP-1 increases GH release and increases [Ca2+]i levels in static monolayer cells of rat pituitary gland, but does not affect cAMP levels .
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Cat. No.: HY-N7057S
CAS No.: 130348-94-6
Synonyms: Pelargonic acid-d17
Nonanoic acid (Pelargonic acid)-d17 is the deuterium labeled Nonanoic acid (HY-N7057). Nonanoic acid is a naturally-occurring saturated fatty acid with nine carbon atoms. Nonanoic acid significantly reduces bacterial translocation, enhances antibacterial activity, and remarkably increases the secretion of porcine β-defensins 1 (pBD-1) and pBD-2 .
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Cat. No.: HY-N7057S2
CAS No.: 1219795-27-3
Synonyms: Pelargonic acid-d4
Nonanoic acid (Pelargonic acid)-d4 is the deuterium labeled Nonanoic acid (HY-N7057). Nonanoic acid is a naturally-occurring saturated fatty acid with nine carbon atoms. Nonanoic acid significantly reduces bacterial translocation, enhances antibacterial activity, and remarkably increases the secretion of porcine β-defensins 1 (pBD-1) and pBD-2 .
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Cat. No.: HY-N7057S1
CAS No.: 134646-27-8
Synonyms: Pelargonic acid-d3
Nonanoic acid (Pelargonic acid)-d3 is the deuterium labeled Nonanoic acid (HY-N7057). Nonanoic acid is a naturally-occurring saturated fatty acid with nine carbon atoms. Nonanoic acid significantly reduces bacterial translocation, enhances antibacterial activity, and remarkably increases the secretion of porcine β-defensins 1 (pBD-1) and pBD-2 .
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Cat. No.: HY-N7057S3
CAS No.: 62689-94-5
Synonyms: Pelargonic acid-d2; Pelargonic acid-d2 (n-Nonanoic acid, C9 )
Nonanoic acid (Pelargonic acid)-d2 is the deuterium labeled Nonanoic acid (HY-N7057) . Nonanoic acid is a naturally-occurring saturated fatty acid with nine carbon atoms. Nonanoic acid significantly reduces bacterial translocation, enhances antibacterial activity, and remarkably increases the secretion of porcine β-defensins 1 (pBD-1) and pBD-2 .
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Cat. No.: HY-P2313
CAS No.: 372146-20-8
Synonyms: HβD-2
Human β-defensin-2 (HβD-2) is an orally active, cysteine-rich antimicrobial peptide secreted by epithelial cells, with antibacterial, antiviral, and immunomodulatory activities. Human β-defensin-2 binds to CCR2, reduces NF-κB phosphorylation, increases CREB phosphorylation, inhibits pro-inflammatory cytokines, induces IL-10, and chemotaxes immune cells through CCR2/CCR6. Human β-defensin-2 reduces smoke-induced neutrophil influx in mouse lungs, downregulates pulmonary pro-inflammatory signaling, promotes bacterial clearance, and improves colitis and asthma cytokine/lung resistance. Human β-defensin-2 can be used in research related to diseases such as inflammatory bowel disease, bacterial infections, viral infections, and atopic asthma .
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Cat. No.: HY-P5603
CAS No.: 455257-02-0
Synonyms: BNBD-12
Target:  

Bacterial

Research Areas:  

Infection

Bovine neutrophil beta-defensin 12 is an antimicrobial peptide derived from bovine neutrophils, which has antibacterial activity against Escherichia coli and Staphylococcus aureus .
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Cat. No.: HY-P2291
Target:  

Bacterial

Research Areas:  

Inflammation/Immunology

Beta-defensin 103 isoform X1, pig is an antimicrobial peptide found in different living organisms, involved in the first line of defense in their innate immune response against pathogens .
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Cat. No.: HY-P2291A
Target:  

Bacterial

Research Areas:  

Inflammation/Immunology

Beta-defensin 103 isoform X1, pig TFA is an antimicrobial peptide found in different living organisms, involved in the first line of defense in their innate immune response against pathogens .
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Cat. No.: HY-P10462
CAS No.: 1403753-45-6
Synonyms: Synthetic anti-inflammatory peptide 15
Target:  

HDAC NF-κB

Research Areas:  

Inflammation/Immunology

SAP15 (Synthetic anti-inflammatory peptide 15) is a synthetic anti-inflammatory peptide consisting of 15 amino acids designed from human beta-defensin 3. SAP15 has the ability to penetrate cells and is able to induce downregulation of intracellular inflammation. SAP15 inhibits inflammation by inhibiting the phosphorylation of HDAC5 and thereby reducing the phosphorylation of NF-κB p65. SAP15 inhibits HDAC5 and NF-κB p65 phosphorylation in LPS (HY-D1056)-induced macrophages. SAP15 increases the expression of aggrecan and type II collagen and decreases the expression of osteocalcin in LPS-induced chondrocytes. SAP15 can be used in the study of inflammation regulation and anti-inflammatory therapy of biomaterials .
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Cat. No.: HY-P10462A
Synonyms: Synthetic anti-inflammatory peptide 15 acetate
Target:  

HDAC NF-κB

Research Areas:  

Inflammation/Immunology

SAP15 (Synthetic anti-inflammatory peptide 15) acetate is a synthetic anti-inflammatory peptide consisting of 15 amino acids designed from human beta-defensin 3. SAP15 acetate has the ability to penetrate cells and is able to induce downregulation of intracellular inflammation. SAP15 acetate inhibits inflammation by inhibiting the phosphorylation of HDAC5 and thereby reducing the phosphorylation of NF-κB p65. SAP15 acetate inhibits HDAC5 and NF-κB p65 phosphorylation in LPS (HY-D1056)-induced macrophages. SAP15 acetate increases the expression of aggrecan and type II collagen and decreases the expression of osteocalcin in LPS-induced chondrocytes. SAP15 acetate can be used in the study of inflammation regulation and anti-inflammatory therapy of biomaterials .
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Cat. No.: HY-P2656
CAS No.: 370570-43-7
Synonyms: hBD-4
Target:  

Bacterial

Research Areas:  

Infection

β-Defensin-4 human is an inducible peptide with a specific salt-sensitive spectrum of antimicrobial activity .
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Cat. No.: HY-P77350
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: DEFB127; beta-defensin 27; Prev. C20orf73; DEFB27; BA530N10.2; Chromosome 20 Open Reading Frame 73; DEF-27; beta-defensin; defensin, beta 127; HBD-27; beta-defensin 127; defensin beta 127; DEFB-27
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P81910
Synonyms: BD1; HBD1; DEFB1; beta-defensin 1; BD-1; hBD-1

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human

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Cat. No.: HY-N7057R
CAS No.: 112-05-0
Synonyms: Pelargonic acid (Standard)
Nonanoic acid (Pelargonic acid) (Standard) is the analytical standard of Nonanoic acid (HY-N7057). This product is intended for research and analytical applications. Nonanoic acid is a naturally-occurring saturated fatty acid with nine carbon atoms. Nonanoic acid significantly reduces bacterial translocation, enhances antibacterial activity, and remarkably increases the secretion of porcine β-defensins 1 (pBD-1) and pBD-2 .
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Cat. No.: HY-P7137
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DEFB103A; defensin-Like Protein; Prev. DEFB103; beta-defensin 103; Prev. DEFB3; BD-3; beta-defensin 3; defensin, beta 103A; DEFB-3; defensin, beta 3; HBD3; beta defensin 3; HBD-3; beta defensin-3; HBP-3; BD3; HBP3; defensin beta 103A; defensin, beta 103
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P7138
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DEFB103A; defensin-Like Protein; Prev. DEFB103; beta-defensin 103; Prev. DEFB3; BD-3; beta-defensin 3; defensin, beta 103A; DEFB-3; defensin, beta 3; HBD3; beta defensin 3; HBD-3; beta defensin-3; HBP-3; BD3; HBP3; defensin beta 103A; defensin, beta 103
Species:  
Mouse
Source:  
E. coli
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