Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
23 Results for "
cholera
" in MedChemExpress (MCE) Product Catalog:
Products (23)
23 Results for "cholera" in MCE Product Catalog:
13
Target:
Research Areas:
Loperamide (ADL 2-1294) is selective and orally active μ opioid receptor agonist with Ki valuess of 3, 48 and 1156 nM against μ, δ and κ opioid receptor, respectively. Loperamide produces antinociception and antihyperalgesia. Loperamide exhibits peripheral selectivity, enhancing fluid, electrolyte, and glucose absorption, reversing PGE2 (HY-101952)- and Cholera toxin (HY-P1446)-induced intestinal secretion, and reducing intestinal motility. Loperamide can be used for the researches of inflammatory pain and protracted diarrhoea .
1
1 Cited Publications
Cat. No.: HY-112624I
CAS No.: 9004-54-0
Synonyms: Dextran 3; Dextran D3; Dextran T3(MW 2400-3600)
1
1 Cited Publications
Synonyms: MIBG sulfate; Iobenguane sulfate
Target:
Research Areas:
m-Iodobenzylguanidine sulfate (MIBG sulfate) is an analogue of the neurotransmitter norepinephrine with antitumor activity. Radioiodinated m-Iodobenzylguanidine sulfate is clinically used as a tumor-targeted radiopharmaceutical in the diagnosis and treatment of adrenergic tumors. m-Iodobenzylguanidine sulfate is a high-affinity substrate for cholera toxin that interferes with cellular mono(ADP-ribosylation) .
Target:
Research Areas:
Sulfaclozine (Sulfachloropyrazine) is an efficacious sulphonamide derivative with antibacterial and anticoccidial effects. Sulfaclozine is commonly used for the treatment of various poultry diseases (particularly, collibacteriosis, fowl cholera and coccidiosis) .
Cat. No.: HY-19285A
CAS No.: 23307-72-4
Synonyms: Sulfachloropyrazine sodium
Target:
Research Areas:
Sulfaclozine sodium (Sulfachloropyrazine sodium) is an efficacious sulphonamide derivative with antibacterial and anticoccidial effects. Sulfaclozine sodium is commonly used for the treatment of various poultry diseases (particularly, collibacteriosis, fowl cholera and coccidiosis) .
Synonyms: CAI-1
Cholera autoinducer 1 (CAI-1) is the major autoinducer in quorum sensing of V. cholerae. Cholera autoinducer 1 accumulates extracellularly as cell density increases, can be detected by V. cholerae, and signals through CqsS to regulate gene expression and inhibit biofilm formation and virulence factor production. Cholera autoinducer 1 can be used for cholera research .
Target:
Research Areas:
Virstatin is an orally effective Vibrio cholerae virulence inhibitor. Virstatin blocks the expression of downstream virulence genes, such as cholera toxin (ctx) and toxin-coregulated pilus (tcpA), at the post-transcriptional level by inhibiting the dimerization of the transcriptional activator ToxT. Virstatin inhibits Vibrio cholerae-induced expression of COX-2 and iNOS, and exerts bactericidal effects at high concentrations. Virstatin can be used for research on cholera .
Cat. No.: HY-P10529
CAS No.: 247185-97-3
Target:
Research Areas:
Cat. No.: HY-401913
CAS No.: 345288-49-5
Target:
Endo CNTinh-03 is inhibitor for the elevation of cAMP and cGMP induced by agonist, such as G protein-coupled receptors, adenylate cyclase, and guanylate cyclase (IC50 is 4 μM). Endo CNTinh-03 inhibits cholera toxin- and Escherichia coli (STa) toxin- induced CFTR chloride current, ameliorates secretory diarrhea in mouse models, and prevents cyst growth in polycystic kidney disease model .
Cat. No.: HY-115846
CAS No.: 2650208-98-1
ML370 is an antibacterial agent. ML370 exerts antibacterial activity by inhibiting the activity of Vibrio cholerae LuxO kinase. ML370 can be used in the research of infectious diseases such as cholera .
Cat. No.: HY-N10511
CAS No.: 67063-78-9
Category:
Natural Products Polysaccharides Endogenous metabolite Disease Research Fields Inflammation/Immunology Saccharides
Target:
Cat. No.: HY-P5555
CAS No.: 1818202-23-1
Leucyl aminopeptidase, Porcine is a metallopeptidase that cleave N-terminal residues from proteins and peptides. Leucyl aminopeptidase serves as transcriptional repressors to control pyrimidine, alginate and cholera toxin biosynthesis, as well as mediate site-specific recombination events in plasmids and phages .
Cat. No.: HY-19285AR
CAS No.: 23307-72-4
Synonyms: Sulfachloropyrazine sodium (Standard)
Research Areas:
Sulfaclozine (sodium) (Standard) is the analytical standard of Sulfaclozine (sodium). This product is intended for research and analytical applications. Sulfaclozine sodium (Sulfachloropyrazine sodium) is an efficacious sulphonamide derivative with antibacterial and anticoccidial effects. Sulfaclozine sodium is commonly used for the treatment of various poultry diseases (particularly, collibacteriosis, fowl cholera and coccidiosis) .
Research Areas:
Sulfaclozine (Standard) is the analytical standard of Sulfaclozine. This product is intended for research and analytical applications. Sulfaclozine (Sulfachloropyrazine) is an efficacious sulphonamide derivative with antibacterial and anticoccidial effects. Sulfaclozine is commonly used for the treatment of various poultry diseases (particularly, collibacteriosis, fowl cholera and coccidiosis) .
Cat. No.: HY-129040AR
CAS No.: 87862-25-7
Synonyms: MIBG sulfate (Standard); Iobenguane sulfate (Standard)
Research Areas:
m-Iodobenzylguanidine (sulfate) (Standard) is the analytical standard of m-Iodobenzylguanidine (sulfate). This product is intended for research and analytical applications. m-Iodobenzylguanidine sulfate (MIBG sulfate) is an analogue of the neurotransmitter norepinephrine with antitumor activity. Radioiodinated m-Iodobenzylguanidine sulfate is clinically used as a tumor-targeted radiopharmaceutical in the diagnosis and treatment of adrenergic tumors. m-Iodobenzylguanidine sulfate is a high-affinity substrate for cholera toxin that interferes with cellular mono(ADP-ribosylation) .
Cat. No.: HY-P704223
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: VC_1456; toxB; ctxB; choleragenoid; cholera enterotoxin gamma chain; cholera enterotoxin B chain; cholera enterotoxin subunit B
Species:
Virus
Source:
HEK293
Cat. No.: HY-B0389F1
Cat. No.: HY-137744
CAS No.: 148821-01-6
Research Areas:
MANT-GppNHp is a competitive adenyl cyclase (AC) inhibitor. MANT-GppNHp is a fluorescently labeled GTP (HY-113225) analogue. MANT-GppNHp interacts with the hydrophobic pocket near the AC catalytic site through its MANT group, thereby directly blocking the binding of the substrate ATP. MANT-GppNHp can be used to study diseases related to the increased activity of AC (such as cholera) .
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
