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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10028 Results for "
cholesterol microcrystals
" in MedChemExpress (MCE) Product Catalog:
Products (10028)
10028 Results for "cholesterol microcrystals" in MCE Product Catalog:
131
131 Publications Verification
Synonyms: Methyl-beta-cyclodextrin
102
102 Cited Publications
Cat. No.: HY-N0322A
Category:
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(Note: This product is a mixture of Cholesterol and Methyl-β-cyclodextrin. The product specifications below only indicate the effective content of Cholesterol.)
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76
76 Cited Publications
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Atorvastatin calcium salt trihydrate is a drug belonging to the statin class of drugs used to lower blood cholesterol levels. Atorvastatin calcium salt trihydrate has unique chemical properties that make it an effective tool in controlling high levels of low-density lipoprotein (LDL) cholesterol and triglycerides in the body, reducing the risk of heart attack and stroke. Atorvastatin calcium salt trihydrate works by inhibiting HMG-CoA reductase, the enzyme responsible for producing cholesterol in the liver.
59
Category:
Infection Macrolide Antibiotics Antifungal Antibiotics Mammalian Cell Culture Microorganism Disease Research Disease Research Fields
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59 Cited Publications
Cat. No.: HY-N6716
CAS No.: 11078-21-0
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Antifungal Antibiotics Other Diseases Antiviral Microorganism Disease Research Disease Research Fields Other Antibiotics
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47
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31
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U18666A, an intra-cellular cholesterol transport inhibitor, inhibits replication of Ebola virus, dengue virus, and human hepatitis C virus .
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31 Cited Publications
Cat. No.: HY-N4000
CAS No.: 11024-24-1
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Plant Digitalis purpurea L. Extract Plantaginaceae Extract Scrophulariaceae Extract Disease Research Fields Cancer Steroids
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30
30 Cited Publications
Cat. No.: HY-17504B
CAS No.: 147098-18-8
Synonyms: ZD 4522 Sodium; X-Plended Sodium; Crestor Sodium
Research Areas:
Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM. Rosuvastatin Sodium potently blocks hERG current with an IC50 of 195 nM . Rosuvastatin Sodium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Sodium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels .
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30 Cited Publications
Cat. No.: HY-17504
CAS No.: 147098-20-2
Synonyms: Rosuvastatin hemicalcium; ZD 4522 Calcium
Research Areas:
Rosuvastatin Calcium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM. Rosuvastatin Calcium potently blocks hERG current with an IC50 of 195 nM . Rosuvastatin Calcium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Calcium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels .
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Research Areas:
Rosuvastatin (ZD 4522) is a competitive HMG-CoA reductase inhibitor with an IC50 of 11 nM. Rosuvastatin potently blocks hERG current with an IC50 of 195 nM, delayed cardiac repolarization, and thereby prolonged action potential durations (APDs) and corrected QT interval (QTc) intervals. Rosuvastatin reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels .
27
Category:
Human Gut Microbiota Metabolites Other disease Disease markers Endogenous metabolite Disease Research Fields Cancer Steroids
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23
23 Cited Publications
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BODIPY-cholesterol is an intrinsically lipophilic, and cell-permeable analog of cholesterol with a fluorescent BODIPY group. BODIPY-cholesterol can be used to monitor sterol uptake and inter-organelle sterol flux in cells. (Excitation/Emission: 505/515 nm) .
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Category:
Human Gut Microbiota Metabolites Other disease Disease markers Metabolic Disease Microorganism Endogenous metabolite Disease Research Fields Steroids
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20
20 Cited Publications
Synonyms: CI-1011; PD-148515
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Avasimibe (CI-1011; PD-148515) is an orally active acyl coenzyme A-cholesterol acyltransferase (ACAT; also called SOAT)) inhibitor with IC50s of 24 and 9.2 µM for ACAT1 and ACAT2, respectively . Avasimibe can be used for the research of prostate cancer .
16
Research Areas:
Cardiovascular Disease Neurological Disease Metabolic Disease Cancer
Pitavastatin (NK-104) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells. Pitavastatin is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Pitavastatin also possesses anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective and reno-protective effects .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
