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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
722 Results for "
cis conformer
" in MedChemExpress (MCE) Product Catalog:
Products (722)
722 Results for "cis conformer" in MCE Product Catalog:
899
899 Publications Verification
Cat. No.: HY-17394
CAS No.: 15663-27-1
Synonyms: cis-Platinum; CDDP; cis-Diaminodichloroplatinum
Research Areas:
Cisplatin (CDDP) is an antineoplastic chemotherapy agent by cross-linking with DNA and causing DNA damage in cancer cells. Cisplatin activates ferroptosis and induces autophagy .
84
84 Cited Publications
Synonyms: 9-cis-Octadecenoic acid; 9Z-Octadecenoic acid
84
84 Cited Publications
Synonyms: Sodium oleate; 9-cis-Octadecenoic acid sodium; 9Z-Octadecenoic acid sodium
15
15 Cited Publications
Synonyms: (-)-Deguelin; (-)-cis-Deguelin
14
14 Cited Publications
Synonyms: 13-cis-Retinoic acid
Target:
11
11 Cited Publications
Synonyms: ML-SI3 (cis/trans mix)
Target:
Research Areas:
ML-SI3 is a mixture of cis/trans ML-SI3 (HY-139426A), which is a TRPML1/2 channel inhibitor with IC50s of 4.7 μM and 1.7 μM, respectively. ML-SI3 also inhibits lysosomal calcium efflux and blocks downstream TRPML1-mediated autophagy. The cis/trans ML-SI3 (HY-139426A) components of ML-SI3 are TRPML2 activators with EC50s of 3.3 μM and 9.4 μM, respectively .
11
Target:
Golgicide A (GCA) is a potent, highly specific, and reversible inhibitor of the cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factors (ArfGEF) GBF1 . Golgicide A drastically reduced replication of coxsackievirus B3 (CVB3) and other human enterovirus species .
7
7 Cited Publications
Synonyms: Selacholeic acid; cis-15-Tetracosenoic acid
Category:
Ketones, Aldehydes, Acids Disease markers Endocrine diseases Plants Other Families Extract Endogenous metabolite
Target:
6
Category:
Terpenoids Diterpenoids Endogenous metabolite Disease Research Fields Inflammation/Immunology Cancer
Target:
4
4 Cited Publications
Synonyms: DGLA; all-cis-8,11,14-Eicosatrienoic acid
Category:
Cardiovascular Disease Ketones, Aldehydes, Acids Disease markers Endocrine diseases Endogenous metabolite Disease Research Fields Inflammation/Immunology
Target:
4
4 Cited Publications
Cat. No.: HY-A0143A
CAS No.: 65881-87-0
Synonyms: DGLA sodium; all-cis-8,11,14-Eicosatrienoic acid sodium
Category:
Target:
4
4 Cited Publications
Synonyms: (R)-Flurbiprofen; MPC7869
Research Areas:
Infection Neurological Disease Inflammation/Immunology Cancer
Tarenflurbil ((R)-Flurbiprofen) is the R-enantiomer of the racemate NSAID Flurbiprofen, Tarenflurbil ((R)-Flurbiprofen) inhibits the binding of [ 3H]9-cis-RA to RXRα LBD with IC50 of 75 μM. Tarenflurbil can be used for Alzheimer's disease research.
3
3 Cited Publications
Target:
Research Areas:
cis-Epoxysuccinic acid is a succinate receptor (SUCNR1/GPR91) agonist. cis-Epoxysuccinic acid inhibits cAMP levels with an EC50 value of 2.7 μM. cis-Epoxysuccinic acid can be used for the research of cardiovascular system .
3
3 Cited Publications
Cat. No.: HY-W004500
CAS No.: 116-31-4
Category:
Human Gut Microbiota Metabolites Microorganisms Terpenoids Other Diseases Diterpenoids Endogenous metabolite Disease Research Fields
Target:
3
2
2
2 Cited Publications
Cat. No.: HY-P70007A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PPIA; Epididymis Secretory Sperm Binding Protein Li 69p; Peptidylprolyl Isomerase A; Peptidylprolyl Isomerase A (Cyclophilin A); CYPA; Peptidyl-Prolyl cis-Trans Isomerase; Peptidyl-Prolyl cis-Trans Isomerase A; T Cell Cyclophilin; Cyclosporin A-Binding Protein; HEL-S-69p; Cyclophilin A; PPIase; Rotamase A; CYPH; PPIase A
Species:
Mouse
Source:
E. coli
2
2 Cited Publications
Synonyms: trans-ML-SI3
Target:
Research Areas:
(rel)-ML-SI3 is one of the active ingredients of ML-SI3 (HY-139426) (another component is (cis)-ML-SI3) that targets three isoforms of TRPML. (rel)-ML-SI3 is an inhibitor of TRPML1 and TRPML3 (IC50=3.1 μM/28.5 μM), and a potent activator of TRPML2 (EC50=3.3 μM) .
2
2 Cited Publications
Cat. No.: HY-W012078R
CAS No.: 838-07-3
Synonyms: 5-Methyldeoxycytidine (Standard)
Category:
1
1 Cited Publications
Cat. No.: HY-16561A
CAS No.: 61434-67-1
Target:
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
