Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
colloidal stability
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "colloidal stability" in MCE Product Catalog:
21
21 Cited Publications
Target:
Research Areas:
ALC-0159 presents highly mobile surface PEG chains in a dense brush-like conformation, which can form a hydrophilic barrier, reduce non-specific protein adsorption and macrophage uptake, improve colloidal stability, prolong in vivo circulation time, and affect the cellular uptake of LNPs. ALC-0159 dissociates from the surface of mRNA-LNPs under long-term mechanical oscillation stress, thereby reducing steric hindrance, inducing mRNA-LNP fusion, increasing particle size, and releasing unencapsulated mRNA .
1
Category:
Ketones, Aldehydes, Acids Other Diseases Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields
Target:
Cat. No.: HY-W011696
CAS No.: 112-90-3
Synonyms: cis-1-Amino-9-octadecene, 80-90%
Synonyms: 16:0 PEG2000 PE ammonium; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] ammonium
DPPE-PEG2000 ammonium (16:0 PEG5000 PE) is a polymer-lipid conjugate and LipoParticle stabilizer with a PEG chain of 5,000 g/mol molecular weight attached to its polar head, and it can be internalized by biological membranes. DPPE-PEG2000 ammonium enables LipoParticle to maintain colloidal stability after 20-fold dilution in PBS or cell culture medium, and prevents aggregate formation during lyophilization and rehydration. DPPE-PEG2000 ammonium helps enhance the non-cytotoxic property of LipoParticle formulations against human osteoblasts. DPPE-PEG2000 ammonium serves as a PEG lipid functional end group for synthesizing liposomes (LPs), is used in the design of conjugated polymer nanoparticles, and applies to research related to bone and joint infections .
Cat. No.: HY-158082B
Synonyms: Tetramethyl rhodamine isothiocyanate glucan, MW 40000
Target:
Research Areas:
TRITC-dextran (Tetramethyl rhodamine isothiocyanate glucan), MW 40000 is a TRITC (HY-D0791)-labeled neutral 40 kDa fluorescent polysaccharide probe. TRITC-dextran, MW 40000 forms a membrane layer on the surface of protocells composed of protamine/folate condensates, and is used to assess membrane fluidity via fluorescence recovery after photobleaching. TRITC-dextran, MW 40000 can also be used to evaluate the anti-bacterial invasion ability and colloidal stability of coated condensates, as well as analyze the permeability of vascular and lymphatic endothelial cell layers .
Cat. No.: HY-144012H
CAS No.: 474922-84-4
Synonyms: 16:0 PEG5000 PE; 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] ammonium
DPPE-PEG5000 (16:0 PEG5000 PE) is a polymer-lipid conjugate and LipoParticle stabilizer with a PEG chain of 5,000 g/mol molecular weight attached to its polar head, and it can be internalized by biological membranes. DPPE-PEG5000 enables LipoParticle to maintain colloidal stability after 20-fold dilution in PBS or cell culture medium, and prevents aggregate formation during lyophilization and rehydration. DPPE-PEG5000 helps enhance the non-cytotoxic property of LipoParticle formulations against human osteoblasts. DPPE-PEG5000 serves as a PEG lipid functional end group for synthesizing liposomes (LPs), is used in the design of conjugated polymer nanoparticles, and applies to research related to bone and joint infections .
Cat. No.: HY-W134328E
CAS No.: 87915-38-6
Synonyms: Dextran blue (MW 70000)
Target:
Research Areas:
Blue dextran (Dextran blue) (MW 70000) is a high-molecular-weight dextran dye and colloidal marker. Blue dextran (MW 70000) exhibits molecular sieve exclusion effects, affinity binding capacity, and biocompatibility and stability. Blue dextran (MW 70000) can be used in research such as human serum protein purification .
Cat. No.: HY-W014130R
CAS No.: 155-84-0
Synonyms: Ac-Arg-OH (Standard)
Cat. No.: HY-187961
CAS No.: 2757286-41-0
Target:
Research Areas:
SARS-CoV-2-IN-123 is a selective SARS-CoV-2 main protease (Mpro) inhibitor with an IC50 of 77 nM and a Kd of 38 nM. SARS-CoV-2-IN-123 exerts its inhibitory effect by blocking the polyprotein processing required for coronavirus replication, and its mechanism of action is independent of covalent cysteine modification or colloidal aggregation. SARS-CoV-2-IN-123 shows broad-spectrum antiviral activity in infected cells, along with favorable metabolic stability, plasma protein binding, and high Caco-2 permeability. SARS-CoV-2-IN-123 can be used for research related to coronavirus infection .
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
