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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
confocal imaging
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "confocal imaging" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-D1540
CAS No.: 2097714-45-7
Synonyms: Cy 5.5 amine; Lumiprobe Cy 5.5 amine
1
Cat. No.: HY-D0154
CAS No.: 80724-20-5
Synonyms: Tetramethylrhodamine-6-isothiocyanate
Cat. No.: HY-D0068
CAS No.: 139346-57-9
Synonyms: 7-Diethylaminocoumarin-3-carboxylic acid, SE
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DEAC, SE (7-Diethylaminocoumarin-3-carboxy acid, SE) is an amine-reactive fluorescent succinimidyl ester (NHS ester) dye that is excitable by a 405 nm laser and emits blue fluorescence. DEAC, SE covalently couples with APTES, incorporates into organosilica colloids through co-condensation with TPM or other silane coupling agents, and can also be used for post-synthetic infiltration labeling of porous titanium dioxide protrusions and covalent binding with surface hydroxyl groups. DEAC, SE is used for fluorescent labeling of colloidal particles and confocal microscopy imaging studies .
Cat. No.: HY-D1991
CAS No.: 906664-68-4
Cat. No.: HY-D2890
CAS No.: 321862-17-3
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5-TAMRA-NHS is a fluorescent dye composed of 5-TAMRA (HY-15942) and a hydroxysuccinimide (NHS) group. The NHS ester of 5-TAMRA-NHS forms amide bonds with primary amino groups, which is used to construct fluorescently labeled probes and conjugates. The labeled products are suitable for fluorescence anisotropy, confocal imaging and flow cytometry assays. 5-TAMRA-NHS can be used for fluorescent labeling and imaging (Ex/Em = 541/567 nm) .
Cat. No.: HY-154850
CAS No.: 2991453-50-8
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F-CRI1 is a STING binding agent. F-CRI1 is radiolabeled with 18F and used as a PET imaging agent to visualize STING expression in tumor microenvironment. F-CRI1 labeled with 19F exhibits fluorescent properties (excitation wavelength: 400 nm) and can be used for flow cytometry and confocal imaging of cells. F-CRI1 can be used for research on colon cancer .
Cat. No.: HY-D2341
CAS No.: 3055969-34-8
Cat. No.: HY-D1439
CAS No.: 172807-13-5
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RH 795 is a lipophilic potentiometric styryl fluorescent dye (Ex/Em = 530 nm/712 nm). RH 795 stains the cell membranes of sensory cells and nerve fibers in living cells that maintain membrane potential, while it shows weak staining effect on supporting cells. RH 795 supports in vivo and in vitro confocal microscopy imaging of intact living inner ear cells and neuronal components. RH 795 can be used in studies related to hearing loss .
Cat. No.: HY-121364
CAS No.: 1416130-06-7
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Bodilisant is a histamine H3 receptor (hH3R) ligand and imaging/labeling agent, with a Ki value of 6.51 nM for hH3R. Bodilisant binds to hH3R to produce strong green fluorescence, localizes to the extracellular membrane without internalization, and generates clear, displaceable fluorescent labeling of hH3R in native human brain tissues. Bodilisant serves as a pharmacological tool to visualize the distribution of hH3R via fluorescence confocal laser scanning microscopy .
Cat. No.: HY-D3379
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Neuro-DiO trifluoromethanesulfonate is a green Fluorescent carbocyanine dye and also a vascular labeling agent. Neuro-DiO trifluoromethanesulfonate can be used for confocal microscopy imaging of cerebral blood vessels in mice (Mus musculus) .
Cat. No.: HY-D3446
CAS No.: 2358677-26-4
Cat. No.: HY-P11850
CAS No.: 1192023-11-2
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Cat. No.: HY-D3164
CAS No.: 1380316-56-2
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TPE-Cy is a fluorescent probe with both aggregation-induced emission (AIE) property and pH-dependent luminescent behavior. TPE-Cy exhibits significant luminescent differences under different acidic and alkaline conditions: it shows moderate to strong red emission with linear variation with pH in acidic environments and within the pH range of 5-7, weak or even no emission within the pH range of 7-10, and switches to blue emission under alkaline conditions. TPE-Cy possesses excellent cell permeability and biocompatibility, enabling accurate ratiometric pH sensing and imaging monitoring in living cells via confocal microscopy, ratiometric analysis and flow cytometry .
Cat. No.: HY-D3573
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AF488 C5 Maleimide is a thiol-reactive Fluorescent dye used to label target proteins and bacterial structures. AF488 C5 Maleimide irreversibly forms covalent thioether conjugates with cysteine thiol groups. AF488 C5 Maleimide stabilizes pre-formed globular low-molecular-weight Tau protein oligomers by blocking cysteine-dependent tau protein aggregation, allowing observation of the internalization process of tau protein oligomers into neuronal cells via confocal microscopy. AF488 C5 Maleimide can label cysteine-modified pili; the outer membrane permeability varies among different bacterial species, allowing imaging via epifluorescence microscopy using a FITC filter set .
Cat. No.: HY-D3128
CAS No.: 2348351-60-8
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Mito-RhFe is a Fluorescent probe for mitochondrial labile Fe³⁺ monitoring via imaging and flow cytometry. This probe is a rhodamine-based construct with a spirolactam fluorescence signaling group and an N2-hydroxyethyldiethylenetriamine chelator; its delocalized positive charge enables mitochondria-targeting ability in live cells, and it exhibits fine cell membrane permeability. In its native state, it exists in the non-fluorescent spirolactam form, but upon binding to Fe³⁺, it undergoes a ring-opening conversion to the fluorescent rhodamine form, triggering a turn-on fluorescent response; this process is reversible, as the addition of the metal chelator TPEN removes Fe³⁺ and converts the probe back to its non-fluorescent spirolactam form, and re-addition of Fe³⁺ restores fluorescence. The probe shows high selectivity for Fe³⁺ over most other metal cations present in living systems, with a ~90-fold fluorescence enhancement upon binding to 20 equiv of Fe³⁺. Mito-RhFe has excitation/emission wavelengths of Ex/Em = 540/578 nm, with an ~8 nm bathochromic shift in emission upon Fe³⁺ binding, and it can also be excited at 543 nm for confocal imaging with emission detected at 570-620 nm[1].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
