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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
126 Results for "
deaminase
" in MedChemExpress (MCE) Product Catalog:
Products (126)
126 Results for "deaminase" in MCE Product Catalog:
11
11 Publications Verification
Synonyms: 2-Chloro-2′-deoxyadenosine; CldAdo; 2CdA
Target:
Research Areas:
Cladribine (2-Chloro-2′-deoxyadenosine), a purine nucleoside analog, is an orally active adenosine deaminase inhibitor. Cladribine functions as an inhibitor of DNA synthesis to block the repair of the damaged DNA. Cladribine can inhibit DNA methylation. Cladribine has anti-lymphoma activity. Cladribine can be used for the research of several hematologic malignancies and multiple sclerosis .
10
Target:
Research Areas:
Pentostatin (CI-825; Deoxycoformycin) is an irreversible inhibitor of adenosine deaminase with Ki of 2.5 pM.
5
5 Cited Publications
Research Areas:
Infection Cardiovascular Disease Neurological Disease Cancer
EHNA hydrochloride is a potent and selective dual inhibitor of cyclic nucleotide phosphodiesterase 2 (PDE2)(IC50=4 μM) and adenosine deaminase (ADA). EHNA hydrochloride exerts a concentration inhibition of the cGMP-stimulated PDE II (cGs-PDE)(IC50:0.8 μM (human), 2 μM (porcine myocardium)), but has smaller inhibitory effect on the unstimulated PDE2 activity. EHNA hydrochloride play roles in mediating diverse pharmacological responses, including antiviral, antitumour and antiarrhythmic effects .
5
5 Cited Publications
Synonyms: NSC309132; 4-Deoxyuridine
Target:
Research Areas:
Zebularine (NSC309132; 4-Deoxyuridine) is a DNA methyltransferase inhibitor. Zebularine also inhibits cytidine deaminase with a Ki of 0.95 μM.
5
5 Cited Publications
Cat. No.: HY-P72975
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: DPP4; DPP IV; Prev. ADCP2; TP103; Prev. CD26; Post-Proline Dipeptidyl Aminopeptidase IV; Adenosine deaminase Complexing Protein 2; Xaa-Pro-Dipeptidylaminopeptidase; T-Cell Activation Antigen CD26; Gly-Pro Naphthylamidase; Dipeptidyl Peptidase IV; Dipeptid
Species:
Human
Source:
HEK293
3
3 Cited Publications
Synonyms: THU; NSC-112907
Target:
Research Areas:
Tetrahydrouridine dihydrate is potent inhibitor of cytidine deaminase (CDA), which competitively blocks the enzyme's active site more effectively than intrinsic cytidine .
3
3 Cited Publications
Cat. No.: HY-15345
Purity: 99.79%
Synonyms: THU dihydrate; NSC-112907 dihydrate
Target:
Research Areas:
Tetrahydrouridine dihydrate (THU dihydrate) is potent inhibitor of cytidine deaminase (CDA), which competitively blocks the enzyme's active site more effectively than intrinsic cytidine.
2
Target:
Research Areas:
Fludarabine-Cl has an inhibitory effect on RNA adenosine deaminase 1 (ADAR1) with an IC50 of 0.87 μM and can be used to prevent and/or study cancer or tumor-related diseases .
2
2 Cited Publications
Cat. No.: HY-W011552R
CAS No.: 2140-79-6
Category:
1
Target:
Research Areas:
Cedazuridine (E7727) (Compound 7a) is an orally active cytidine deaminase (CDA) inhibitor with an IC50 value of 0.4 μM. Cedazuridine can be used for cancer research .
1
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Research Areas:
Adenosine deaminase (RnADA) (EC 3.5.4.4) is an enzyme that catalyzes the irreversible deamination of adenosine and 2'-deoxyadenosine to inosine and 2'-deoxyinosine, respectively.
1
1
1 Cited Publications
Target:
Research Areas:
AMPD2 inhibitor 1 is an adenosine monophosphate deaminase 2 (AMPD2) inhibitor, used in the research of sugar craving, salt craving, umami craving, and addictions including agent, tobacco, nicotine and alcohol addictions.
1
1 Cited Publications
Cat. No.: HY-P70025
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CTH; Cysteine Desulfhydrase; Cystathionine Gamma-Lyase; Gamma-Cystathionase; CSE; CGL; Cystathionase (Cystathionine Gamma-Lyase); Homoserine Dehydratase; Cysteine-Protein Sulfhydrase; Homoserine deaminase; Homocysteine Desulfhydrase
Species:
Human
Source:
E. coli
1
1
1 Cited Publications
Cat. No.: HY-P70017
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DPP4; DPP IV; Prev. ADCP2; TP103; Prev. CD26; Post-Proline Dipeptidyl Aminopeptidase IV; Adenosine deaminase Complexing Protein 2; Xaa-Pro-Dipeptidylaminopeptidase; T-Cell Activation Antigen CD26; Gly-Pro Naphthylamidase; Dipeptidyl Peptidase IV; Dipeptid
Species:
Human
Source:
HEK293
Cat. No.: HY-W011256
CAS No.: 37063-35-7
Research Areas:
Adenosine 2',3'-cyclic phosphate sodium is a 2',3'-cyclic purine nucleotide. Adenosine 2',3'-cyclic phosphate sodium is deaminated by the adenosine deaminase. Adenosine 2',3'-cyclic phosphate sodium can be degrade to 2'-AMP and 3'-AMP .
Cat. No.: HY-W011552
CAS No.: 2140-79-6
Target:
Research Areas:
2'-O-Methyladenosine, a methylated adenine residue is found in urine of normals as well as in urine of adenosine deaminase (ADA) deficient patients. 2'-O-Methyladenosine exhibits unique hypotensive activities .
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Research Areas:
L-Adenosine is a metabolically stable enantiomeric analog and also is a potential probe. L-Adenosine has weakly inhibitory adenosine deaminase (ADA) activity with an Ki value of 385 μM. L-Adenosine can be used for the research of adenosine uptake and accumulation .
Synonyms: dATP trisodium
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
