11 Results for "

helminth

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "helminth" in MCE Product Catalog:

17
17 Cited Publications
Cat. No.: HY-B0217
CAS No.: 55981-09-4
Synonyms: NTZ; NSC 697855
Research Areas:  

Infection Cancer

Nitazoxanide (NTZ), an anthelmintic agent, exhibits a broad spectrum of activities against a wide variety of helminths, protozoa, and enteric bacteria infecting animals and humans. Nitazoxanide inhibits Giardia lamblia trophozoite proliferation in axenic culture with an IC50 of 2.4 μM . Nitazoxanide can be used for the research of parasitic gastroenteritis. Nitazoxanide shows anti-Japanese encephalitis virus (JEV) activity in a mouse model .
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Cat. No.: HY-B0263S1
CAS No.: 2140327-29-1
Synonyms: 2-(4-Thiazolyl)benzimidazole-13C6
Thiabendazole- 13C6 is the 13C6 labeled Thiabendazole. Thiabendazole inhibites the mitochondrial helminth-specific enzyme, fumarate reductase, with anthelminthic property.
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Cat. No.: HY-138502A
CAS No.: 89141-50-4
Target:  

Parasite

Research Areas:  

Infection

Melarsomine dihydrochloride is a trivalent arsenical compound used as an adulticide. Melarsomine dihydrochloride can be used for the reserach of canine heartworm disease and other helminth infections .
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Cat. No.: HY-N10184
CAS No.: 540770-33-0
Synonyms: FKI-0550
Paecilaminol is an amino alcohol and NADH-fumarate reductase inhibitor (IC50 = 5.1 μM against Ascaris suum) that also inhibits both helminth and mammalian mitochondrial complexes I and III, exhibiting antifungal, antibacterial, nematocidal, insecticidal, and cancer cell growth-inhibitory activities. Paecilaminol can be used in research on helminth infections .
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Cat. No.: HY-138502
CAS No.: 128470-15-5
Target:  

Parasite

Research Areas:  

Infection

Melarsomine is a trivalent arsenical compound used as an adulticide. Melarsomine can be used for the reserach of canine heartworm disease and other helminth infections .
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Cat. No.: HY-121429
CAS No.: 124-28-7
Purity:  ≥97.0%
Synonyms: N,N-Dimethyloctadecan-1-amine
Target:  

Parasite

Research Areas:  

Infection

Dymanthine (N,N-Dimethyloctadecan-1-amine) is a broad-spectrum intestinal anthelmintic. Dymanthine is used in research related to various helminth infections (Ascaris lumbricoides, Trichuris trichiura, and Ancylostoma duodenale) .
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Cat. No.: HY-B0217R
CAS No.: 55981-09-4
Synonyms: NTZ (Standard); NSC 697855 (Standard)
Nitazoxanide (Standard) is the analytical standard of Nitazoxanide. This product is intended for research and analytical applications. Nitazoxanide (NTZ), an anthelmintic agent, exhibits a broad spectrum of activities against a wide variety of helminths, protozoa, and enteric bacteria infecting animals and humans. Nitazoxanide inhibits Giardia lamblia trophozoite proliferation in axenic culture with an IC50 of 2.4 μM . Nitazoxanide can be used for the research of parasitic gastroenteritis. Nitazoxanide shows anti-Japanese encephalitis virus (JEV) activity in a mouse model .
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Cat. No.: HY-164052
CAS No.: 556055-08-4
Target:  

Parasite

Research Areas:  

Infection

Antiparasitic agent-23 (compound 14) is an anthelmintic and insecticide that inhibits insect or helminth parasitism .
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Cat. No.: HY-158423
CAS No.: 615281-26-0
Research Areas:  

Infection

NPD8790 is a species selective mitochondrial respiratory complex I inhibitor with an IC50 of 2.4 µM for C. elegans complex I. NPD8790 is more selective for nematode species mitochondria than human, bovine, and mouse mitochondria. NPD8790 is an anthelmintic that kills adult soil-transmitted helminths .
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Cat. No.: HY-B2180
CAS No.: 2893-78-9
Research Areas:  

Infection

Dichloroisocyanurate sodium is a synthetic organochlorine compound belonging to triazine derivatives, and is commonly used as a disinfectant and biocide. Dichloroisocyanurate sodium can release hypochlorous acid to inactivate waterborne bacteria, viruses, helminths and protozoa, and can act as a hypochlorous acid reservoir to provide sustained biocidal protection .
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Cat. No.: HY-L082
682 compounds

A parasite is an organism that lives on or in a host organism and gets its food from or at the expense of its host. Parasites of humans include protozoans, helminths, and ecto-parasites (organisms that live on the external surface of a host). They are responsible for many diseases and are transmitted to their hosts most often through the ingestion of contaminated food, water or through the bite of an arthropod (e.g., a fly or tick), which can act as an intermediate host and as a vector. Parasitic diseases of humans are a major global health problem causing significant morbidity and mortality, especially in developing countries. Each year there are hundreds of millions of people infected with disease-causing parasites, particularly in tropical and subtropical regions of the world, resulting in an estimated one million deaths. Therefore, there is a dire need of novel anti-parasitic drugs.

MCE has a unique collection of 682 compounds with validated anti-parasitic activity which offer researchers an opportunity to screen novel anti-parasitic targets.

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