Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
human FKBP12
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "human FKBP12" in MCE Product Catalog:
1
1 Cited Publications
mTOR inhibitor-8 is an mTOR inhibitor and autophagy inducer. mTOR inhibitor-8 inhibits the activity of mTOR via FKBP12 and induces autophagy of A549 human lung cancer cells .
Cat. No.: HY-190160
CAS No.: 164159-88-0
Target:
Research Areas:
Antascomicin B is a macrocyclic natural product that binds purified human FKBP12, FKBP12.6, FKBP51, and FKBP52. Antascomicin B acts as a molecular glue that binds the FK1 domain to stabilize the FKBP51-Akt1 complex, with a Kd of 6.7 nM for human FKBP51, independent of AKT activation status and Hsp90 binding .
Cat. No.: HY-P76345A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FKBP1A; Calstabin-1; Prev. FKBP1; FKBP12C; FKBP-12; FKBP-1A; FKBP12; FK506-Binding Protein, T-Cell, 12-KD; PPIASE; FK506-Binding Protein 1A (12kD); PKC12; Protein Kinase C Inhibitor 2; Peptidyl-Prolyl Cis-Trans Isomerase FKBP1A; FK506 Binding Protein 1A;
Species:
Human
Source:
E. coli
Cat. No.: HY-P76345
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FKBP1A; Calstabin-1; Prev. FKBP1; FKBP12C; FKBP-12; FKBP-1A; FKBP12; FK506-Binding Protein, T-Cell, 12-KD; PPIASE; FK506-Binding Protein 1A (12kD); PKC12; Protein Kinase C Inhibitor 2; Peptidyl-Prolyl Cis-Trans Isomerase FKBP1A; FK506 Binding Protein 1A;
Species:
Human
Source:
E. coli
Cat. No.: HY-P703567
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Serine/threonine-protein kinase mTOR; EC:2.7.11.1; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin (mTOR); Mechanistic target of rapamycin; Rapamycin and FKBP12 ta
Species:
Human
Source:
Sf9 insect cells
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
