8 Results for "

immunotoxin

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "immunotoxin" in MCE Product Catalog:

Cat. No.: HY-P991550
CAS No.: 505393-48-6

Target:  

CD22

Research Areas:  

Cancer

RFB4 is an anti-CD22 monoclonal antibody. RFB4 can be fused with Pseudomonas aeruginosa exotoxin (PE38) via disulfide bonds to construct recombinant immunotoxins, such as RFB4 (dsFv)-PE38. RFB4 is applicable to the research of cancers including lymphoma .
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Cat. No.: HY-P99650
CAS No.: 2367001-70-3
Synonyms: WT1

Research Areas:  

Cancer

Grisnilimab (WT1) is an IgG2a monoclonal antibody targeting CD7. Grisnilimab only binds to lymphoid tissues and T lymphocytes, with no off-target binding to normal tissues. Grisnilimab can be used to synthesize the immunotoxin WT1-SMPT-dgRTA, which exerts cytotoxic effects on T-lymphoblastic leukemia cells. Grisnilimab is applicable to relevant research on leukemia .
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Cat. No.: HY-P99034
CAS No.: 1622075-65-3

Target:  

CD22

Research Areas:  

Cancer

Moxetumomab is a CD22-targeting monoclonal antibody that forms the component of Moxetumomab Pasudotox, a recombinant CD22-targeting immunotoxin. Moxetumomab binds to CD22 on malignant B cells and delivers the PE38 toxin domain to tumor cells. Moxetumomab can be used in research on relapsed or refractory hairy cell leukemia .
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Cat. No.: HY-P99685
CAS No.: 1622327-37-0
Synonyms: IMGN289; J2898A-SMCC-DM1
Research Areas:  

Cancer

Laprituximab emtansine (IMGN-289) is an immunotoxin targeting HER1. Laprituximab emtansine is an EGFR antibody-drug conjugate (ADC) consisting of the J2898A antibody, DM1 (anti-microtubule agent) and the SMCC thioether linker. Laprituximab emtansine can be used for cancer research .
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Cat. No.: HY-P991573

Target:  

EGFR

Research Areas:  

Cancer

Anti-EGFR Antibody (D2C7) is a monoclonal antibody against EGFR. The recombinant immunotoxin D2C7-(scdsFv)-PE38KDEL constructed based on Anti-EGFR Antibody (D2C7) has antineoplastic activity in glioblastoma models .
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Cat. No.: HY-114527
CAS No.: 102660-13-9
Research Areas:  

Cancer

TPMP-I-2 is an anticancer agent that induces cancer cell lines Apoptosis and decreases protein levels of stearoyl-CoA desaturase. TPMP-I-2 prolongs the survival time of nude rats in a simulated micrometastatic cervical cancer model and reduces tumor growth in a breast cancer model in nude mice combined with immunotoxins .
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Cat. No.: HY-133543A
CAS No.: 153569-12-1
Research Areas:  

Others

SPDP-sulfo sodium is a water-soluble heterobifunctional crosslinker containing a cleavable disulfide bond . SPDP-sulfo sodium forms a stable amide bond with primary amines through the Sulfo-NHS ester at one end, and reacts with sulfhydryl groups via the 2-pyridyldithiol group at the other end, thereby constructing a disulfide crosslink that can be specifically cleaved in the intracellular reducing microenvironment. SPDP-sulfo sodium can be widely used in the research and construction of ADCs and immunotoxins, receptor-mediated nano-targeted carrier delivery systems, and enzyme-antibody/antigen labels .
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Cat. No.: HY-P992209

Research Areas:  

Cancer

Anti-CD318/CDCP1 Antibody (25A11) is an anti-CDCP1 antibody. Anti-CD318/CDCP1 Antibody (25A11) drives the internalization of antibody-CDCP1 complexes, inhibits cancer cell migration and invasion, and blocks downstream migration/invasion signaling pathways. When conjugated with saponin, Anti-CD318/CDCP1 Antibody (25A11) mediates the killing of prostate cancer cells. When conjugated with saponin, this antibody acts as an immunotoxin to inhibit the growth and metastasis of primary prostate tumors in mouse xenograft models. Anti-CD318/CDCP1 Antibody (25A11) is applicable to prostate cancer-related research .
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