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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
labile copper
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "labile copper" in MCE Product Catalog:
Cat. No.: HY-W753658
CAS No.: 1335151-56-8
Research Areas:
Coppersensor-3 is a Cu (I)-selective fluorescent probe, λabs 540 nm, λem 548 nm. Coppersensor-3 detects basal levels of labile Cu (I) in living cells and produces fluorescence turn-on by inhibiting photoinduced electron transfer. Coppersensor-3 is useful for studies related to copper homeostasis and copper transport .
Cat. No.: HY-D3282
CAS No.: 2158208-42-3
Cat. No.: HY-D3232
Target:
Research Areas:
BODIPYS1 is a near-infrared ratiometric fluorescent sensor and labile copper detection probe. BODIPYS1 possesses excitation-ratiometric copper-sensing capability, with the ratio of near-infrared emission under 600 nm excitation (710 nm) to that under 660 nm excitation, Fex600/Fex660, increasing from 2.8 to 10.7. BODIPYS1 is capable of tracking labile copper ions in mice .
Cat. No.: HY-D3241
CAS No.: 3133651-84-7
Target:
Research Areas:
CD649.2 is a red-emitting copper-targeted acylimidazole-reactive Fluorescent probe and a highly specific Cu 2+ detection reagent. CD649.2 enables visualization of labile Cu 2+ pools and their dynamic changes in living cells .
Cat. No.: HY-W190928
CAS No.: 1398044-56-8
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Research Areas:
2-(Azido-PEG2-amido)-1,3-bis-(tert-butyldimethylsilanoxy)propane is a PEG linker containing a TBDMS acid labile, alcohol protecting group. The azide group is able to participate in copper-catalyzed Click Chemistry reactions with alkynes, DBCO and BCN to generate triazole linkages. The hydrophilic PEG linker increases the solubility properties of compounds in aqueous media.
Cat. No.: HY-W783351
CAS No.: 1416808-87-1
Synonyms: coppersensor 790 acetoxymethyl ester
Target:
Research Areas:
CS790AM (Coppersensor 790 acetoxymethyl ester) is a cell-permeable, Cu +-targeted near-infrared fluorescent probe (λabs=760 nm, λem=790 nm) applicable to live cells. CS790AM can cross lipophilic cell membranes, and is converted into negatively charged CS790 under the action of intracellular esterases to be retained, thus enabling highly sensitive, reversible "turn-on" detection of labile Cu + pools in live cells and mice. CS790AM possesses excellent biocompatibility and selectivity, avoids interference from other metal ions, shows no obvious toxicity, and can be rapidly cleared. CS790AM allows long-term longitudinal monitoring of individual mice, visualizes copper levels in internal organs and isolated livers, and effectively evaluates abnormal copper accumulation in Wilson's disease models (Atp7b -/-) as well as dynamic changes after chelator treatment. CS790AM can be used for research on Wilson's disease and related copper metabolic disorders .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
