3 Results for "

myometrium

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "myometrium" in MCE Product Catalog:

Cat. No.: HY-106389
CAS No.: 96346-61-1
Synonyms: ZK 98299
Target:  

Progesterone Receptor

Research Areas:  

Cancer

Onapristone is a progesterone receptor antagonist, with Kds of 11.6 nM and 11.90 nM for human endometrium and myometrium progesterone receptor in saturation analysis. Onapristone has antitumor activity .
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Cat. No.: HY-N20642
CAS No.: 152110-04-8
Humilinolide A is a limonoid compound. Humilinolide A can be isolated from Swietenia humilis. Humilinolide A binds to estrogen-dependent receptors on the plasma membrane of the myometrium, thereby triggering uterine contraction responses. Humilinolide A induces irreversible, concentration-dependent increases in the tension, amplitude and frequency of smooth muscle contraction. Humilinolide A inhibits radicle growth of barnyard grass (Echinochloa crus-galli) with a IC50 of 99.0 µg/mL. Humilinolide A exhibits antifeedant activity. Humilinolide A can be used in studies related to gastrointestinal motility regulation and reproductive smooth muscle function .
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Cat. No.: HY-165456
CAS No.: 134892-42-5
Research Areas:  

Endocrinology

AGN-190851 is a potent and selective agonist of α2-adrenergic receptor (α2 adrenoceptor). AGN-190851 induces dose-dependent water diuresis in rats, and inhibits vasopressin V2 receptor in a species-dependent manner in vitro, thereby suppressing cAMP production. AGN-190851 enhances the contraction of porcine myometrium. AGN 190851 can be used in studies on renal diuretic mechanisms, pharmacology of α2-adrenergic receptor subtypes, and parturition .
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