Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
orthogonal labeling
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "orthogonal labeling" in MCE Product Catalog:
Cat. No.: HY-D2335
Cat. No.: HY-D2955
CAS No.: 2432950-51-9
Synonyms: CLIP-AZIDE
Cat. No.: HY-134386
CAS No.: 944834-43-9
Synonyms: N6-(Phenethyl)-ATPγS
Target:
Research Areas:
6-PhEt-ATP-γ-S (N6-(Phenethyl)-ATPγS) is a bulky ATP analog probe carrying a thiophosphate group. 6-PhEt-ATP-γ-S, as an orthogonal phosphate donor, is specifically utilized by mutant-sensitive kinases such as CDK12-AS and Slt2-as to label their direct substrate proteins. 6-PhEt-ATP-γ-S specifically binds to the enlarged pocket of mutant kinases via its bulky side chain (avoiding wild-type), and covalently labels substrates through thiophosphorylation. 6-PhEt-ATP-γ-S can be used for kinase-substrate profiling studies .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
