2 Results for "

zinc-dependent proteases

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "zinc-dependent proteases" in MCE Product Catalog:

Cat. No.: HY-P3202
CAS No.: 79955-99-0
Synonyms: MMP-3; Stromelysin-1
Target:  

MMP

Research Areas:  

Neurological Disease

Matrix metalloproteinase 3 (MMP-3) is a member of the class of zinc-dependent proteases that can degrade the extracellular matrix (ECM). Matrix metalloproteinase 3 palys an important role in the neuronal apoptotic process as well as in neuroinflammation. Matrix metalloproteinase 3 can be used in the study of neurodegenerative diseases including Alzheimer’s disease (AD) and Parkinson’s disease (PD) .
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Cat. No.: HY-11037
CAS No.: 1112169-64-8
Target:  

MMP

Research Areas:  

Inflammation/Immunology

MMP13-IN-7 is an orally active MMP-13 inhibitor with a Ki value of 1.5 nM. MMP13-IN-7 targets the zinc-dependent protease MMP-13 that cleaves type II collagen. MMP13-IN-7 reduces elevated type II collagen neoepitope levels and the severity of osteoarthritis-like joint lesions in a canine meniscectomy model. MMP13-IN-7 can be used for research on osteoarthritis .
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