4 Results for "

B. subtilis DNA

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "B. subtilis DNA" in MCE Product Catalog:

Cat. No.: HY-W354851
CAS No.: 67494-15-9
Pisiferic acid is a blood-brain barrier-permeable Kv1.1/Kv1.2 opener and Antibacterial agent. Pisiferic acid has no activity against KCNQ2/3, hERG, or Kv2.1. Pisiferic acid inhibits Perilipin1 and PPARγ protein expression. Pisiferic acid activates PP2C, inhibits PP2B/calcineurin, and induces Apoptosis/Caspase-3/7. Pisiferic acid inhibits macromolecule synthesis in Proteus vulgaris and inhibits DNA/lipid/peptidoglycan synthesis in Bacillus subtilis. Pisiferic acid has antibacterial effects against Proteus vulgaris, Staphylococcus aureus, and Bacillus subtilis. Pisiferic acid can be used for research on episodic ataxia type 1, Kv1.2 loss-of-function channelopathy, obesity, and acute promyelocytic leukemia .
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Cat. No.: HY-P10230
CAS No.: 207410-26-2
Target:  

Bacterial

Research Areas:  

Infection

Sublancin is an antimicrobial peptide, which inhibits DNA replication, transcription and translation, without affecting membrane integrity. Sublancin suppresses glucose uptake for the competition of phosphotransferase system (PTS). Sublancin inhibits B. subtilis strain 168 ΔSPβ with MIC of 0.312 μM .
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Cat. No.: HY-175539
Research Areas:  

Infection

DNA gyrase/Topo IV-IN-2 (Compound AK19) is an antibacterial agent with IC50 values of 0.783 μM and 7.136 μM against E. coli DNA gyrase and topoisomerase IV, respectively. DNA gyrase/Topo IV-IN-2 exhibits broad-spectrum antibacterial efficacy against both Gram-positive and Gram-negative pathogens. DNA gyrase/Topo IV-IN-2 can inhibit the biofilms of B. subtilis and MRSA, with an MIC of 1.9 μM against both B. subtilis and MRSA. DNA gyrase/Topo IV-IN-2 can be used in research related to anti-drug-resistant bacterial drugs .
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Cat. No.: HY-187902
CAS No.: 75057-96-4
Novclobiocin 101 is a non-halogenated chloro Novobiocin (HY-B0425) analog and a DNA gyrase inhibitor (IC50 0.9 μM) that also inhibits DNA topoisomerase IV (IC50 6 μM). Novclobiocin 101 inhibits gyrase-catalyzed DNA supercoiling and topoisomerase IV-mediated DNA decatenation. Novclobiocin 101 exhibits antibacterial activity against Bacillus subtilis and shows cytotoxicity against small cell lung cancer cells. Novclobiocin 101 can be used for research on bacterial and fungal infections as well as cancer .
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