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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
Candida auris
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "Candida auris" in MCE Product Catalog:
Target:
Research Areas:
VT-1598 is an orally active and selective fungal inhibitor targeting CYP51. VT-1598 shows anti-fungal activity against Candida auris . VT-1598 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-168077
CAS No.: 480452-24-2
Antibiofilm agent-12 (Compound C13) is an antifungal agent that belongs to the class of carbazate derivatives. Antibiofilm agent-12 exhibits significant antifungal activity against Candida auris, with a MIC90 of 237.9 μM. By inhibiting the drug efflux pump activity of Candida auris and promoting ergosterol depletion, Antibiofilm agent-12 hinders biofilm formation and reduces the metabolic flexibility of Candida auris. Additionally, Antibiofilm agent-12 demonstrates antifungal activity in a Candida auris-infected C. elegans model .
Cat. No.: HY-P992076
Cat. No.: HY-155712
CAS No.: 2925307-57-7
Antifungal agent 70 (compound 13) is a dihydroeugenol-imidazole against multi-resistant Candida auris (MIC: 36.4 μM). Antifungal agent 70 shows antifungal activity .
Cat. No.: HY-169919
CAS No.: 3020690-76-7
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HDM-IN-1 (Compound A4) is an inhibitor for fungal histone demethylase (HDM), that inhibits the H3K27me3 in Cryptococcus neoformans and in Candida auris with IC50s of 134 and 12 nM. HDM-IN-1 exhibits inhibitory efficacy against C. neoformans and C. auris with MIC80 of 0.5-2 μg/mL, through inhibition of the biofilm and capsule formation. HDM-IN-1 exhibits antifungal activity in ICR mouse model .
Cat. No.: HY-155545
Antifungal agent 60 (compound 16) is an inhibitor of ergosterol biosynthesis with broad-spectrum antifungal activity. Antifungal agent 60 inhibits 7 human pathogenic fungal species, 2 fluconazole-resistant C. albicans isolates and 2 multi-drug resistant Candida auris isolates. Antifungal agent 60 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-135713
CAS No.: 219714-96-2
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Penoxsulam is an acetolactate synthase (ALS) inhibitor herbicide. Penoxsulam inhibits Candida auris acetohydroxyacid synthase (AHAS) with a Ki value of <32 nM. Penoxsulam can be used for postemergence control of annual grasses, sedges, and broadleaf weeds in rice culture. Penoxsulam can be used for the study of Candida auris infections .
Cat. No.: HY-N19241
CAS No.: 876152-18-0
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Cat. No.: HY-N19184
CAS No.: 2900278-39-7
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Cat. No.: HY-184894
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RK-1205-I is a protein phosphatase 2A (PP2A) inhibitor and fungal growth inhibitor. RK-1205-I inhibits PP2A activity in fungal cells, leading to the accumulation of Ser/Thr phosphorylated proteins. RK-1205-I acts as a morphoregulator and induces unique morphological changes in filamentous fungi. RK-1205-I inhibits the growth of various fungi, including Aspergillus oryzae, Aspergillus fumigatus and Candida auris. RK-1205-I can be used for the research of fungal infections .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
