10 Results for "

Delta strain

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "Delta strain" in MCE Product Catalog:

Cat. No.: HY-138354A
CAS No.: 72978-16-6
Purity:  98.87%
Synonyms: Pyr2C sodium
Target:  

Drug Intermediate

Research Areas:  

Infection

Δ1-Pyrroline-2-carboxylic acid (Pyr2C) sodium is a cyclic imino acid involved in proline metabolism. Within cells, Δ1-Pyrroline-2-carboxylic acid sodium can be directly reduced to proline, supporting the growth of proline-auxotrophic strains of Escherichia coli. Δ1-Pyrroline-2-carboxylic acid sodium also serves as an intermediate in organic synthesis and can be used to synthesize L-pipecolic acid (HY-W012734) .
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Cat. No.: HY-138354
CAS No.: 2139-03-9
Synonyms: Pyr2C
Target:  

Drug Intermediate

Research Areas:  

Infection

Δ1-Pyrroline-2-carboxylic acid (Pyr2C) is a cyclic imino acid involved in proline metabolism. Within cells, Δ1-Pyrroline-2-carboxylic acid can be directly reduced to proline, supporting the growth of proline-auxotrophic strains of Escherichia coli. Δ1-Pyrroline-2-carboxylic acid also serves as an intermediate in organic synthesis and can be used to synthesize L-pipecolic acid (HY-W012734) .
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Cat. No.: HY-157778
CAS No.: 2952554-69-5
Target:  

SARS-CoV Virus Protease

Research Areas:  

Infection

MK-7845 is an orally active and selective SARS-CoV-2 3CL protease (M pro) inhibitor with an IC50 of 8.7 nM. MK-7845 forms a reversible covalent adduct with the catalytic cysteine, interacting with histidine through its difluorobutyl P1 group. MK-7845 exhibits antiviral activity against the WA1/2020 wild-type, Delta, and Omicron strains. MK-7845 demonstrates in vivo efficacy in a mouse SARS-CoV-2 infection model, reducing lung viral load and preventing body weight loss. MK-7845 can be used for research related to SARS-CoV-2 viral infection .
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Cat. No.: HY-174385
Target:  

SARS-CoV

Research Areas:  

Infection

SARS-CoV-2-IN-114 (Compound 36) is an antiviral agent. SARS-CoV-2-IN-114 exhibits significant antiviral activity against both the SARS-CoV-2 original strain and the Delta variant. SARS-CoV-2-IN-114 has an EC50 of 0.29 μM for inhibiting CPE of the SARS-CoV-2 original strain, and that for the Delta variant is 5.77 μM. SARS-CoV-2-IN-114 has low cytotoxicity and can be used in coronavirus research .
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Cat. No.: HY-149314
Target:  

SARS-CoV

Research Areas:  

Infection

SARS-CoV-2-IN-47 (Compound 13) is a SARS-CoV-2 inhibitor (IC50: 0.77 μM against Omicron BA.1, 0.93 μM against Delta strain). SARS-CoV-2-IN-47 can be used for antiviral research .
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Cat. No.: HY-178291
CAS No.: 104959-32-2
Target:  

SARS-CoV

Research Areas:  

Infection

2-Chloro-2′-deoxyadenosine monophosphate is an anticoronavirus agent. It exhibits significant inhibitory effects against wild-type novel coronavirus, novel coronavirus variants (Beta, Delta, and Omicron strains), and other coronaviruses such as human coronavirus 229E, human coronavirus OC43, human coronavirus NL63, and mouse coronavirus MHV .
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Cat. No.: HY-P10872
Target:  

SARS-CoV

Research Areas:  

Infection

P315V3 is an pan inhibitor for coronavirus, that inhibits SARS-CoV-2 prototypePT, Delta, BA.1 and BA.4 strain with IC50s of 10.9, 8.9, 8.6, and 2.7 nM. P315V3 exhibits cytotoxicity in Vero cell with CC50 of 4.3 μM. P315V3 exhibits anti-infectious efficacy in mouse models .
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Cat. No.: HY-117192
CAS No.: 1052515-37-3
Target:  

HSP Fungal

Research Areas:  

Infection

NSC145366 monohydrochloride is a Hsp90 C-terminal inhibitor. NSC145366 monohydrochloride directly interacts with the C-terminus of Hsp90 and inhibits its chaperone activity. NSC145366 monohydrochloride strongly inhibits the growth of Saccharomyces cerevisiae cog7Δ and cog8Δ strains .
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Cat. No.: HY-P703438
Synonyms: RCAP_rcc01447; hemA; Delta-aminolevulinate synthase; Delta-ALA synthase; 5-aminolevulinic acid synthase; EC:2.3.1.37; 5-aminolevulinate synthase; hemA; Delta-ALA synthase; Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003); Acyltransferase
Species:  
Others
Source:  
E. coli
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Cat. No.: HY-181661
Target:  

SARS-CoV Virus Protease

Research Areas:  

Infection

YL1004 is a potent, selective and orally active noncovalent inhibitor of SARS-CoV-2 papain-like protease (PL pro). YL1004 shows an IC50 of 17.5 nM and a Ki of 2.3 nM against PL pro, with an in vitro anti-SARS-CoV-2 EC50 of 0.08 μM-1.37 μM. YL1004 suppresses the proteolytic activity of PL pro and blocks its deubiquitinating and deISGylating effects to restore host innate antiviral immune signaling. YL1004 inhibits the replication of wild-type, Delta, Omicron variants and nirmatrelvir-resistant strains of SARS-CoV-2. YL1004 can be used for the research of COVID-19 (SARS-CoV-2 infection) .
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