322 Results for "

Protecting group

" in MedChemExpress (MCE) Product Catalog:
Products (322)

322 Results for "Protecting group" in MCE Product Catalog:

20
20 Publications Verification
Cat. No.: HY-120501
CAS No.: 1202764-53-1
Purity:  99.37%
Target:  

NF-κB

Research Areas:  

Inflammation/Immunology

B022 is a potent and selective NF-κB-inducing kinase (NIK) inhibitor (Ki of 4.2 nM; IC50=15.1 nM). B022 protects liver from toxin-induced inflammation, oxidative stress, and injury . B022 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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10
10 Cited Publications
Cat. No.: HY-B1142
CAS No.: 940-69-2
Synonyms: (±)-α-Lipoamide; DL-Lipoamide; DL-6,8-Thioctamide
Lipoamide ((±)-α-Lipoamide) is a monocarboxylic acid derivative of a neutral amide, formed by the condensation of the carboxyl group of lipoic acid and ammonia. Lipoamide protects against oxidative stress-mediated neuronal cell damage and also acts as a coenzyme to transfer acetyl groups and hydrogen during pyruvate deacylation. Lipoamide also stimulates mitochondrial biogenesis in adipocytes through the endothelial NO synthase-cGMP-protein kinase G signaling pathway .
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4
4 Cited Publications
Cat. No.: HY-18941C
Synonyms: LY354740 hydrochloride; Eglumetad hydrochloride
Target:  

mGluR

Research Areas:  

Neurological Disease

Eglumegad (LY354740) hydrochloride is a highly potent and selective group II (mGlu2/3) receptor agonist with IC50s of 5 and 24 nM on transfected human mGlu2 and mGlu3 receptors, respectively. Eglumegad hydrochloride protects neurons from NMDA toxicity. Eglumegad hydrochloride has anxiolytic- and antipsychotic-like effects .
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1
1 Cited Publications
Cat. No.: HY-W013081
CAS No.: 132327-80-1
Fmoc-Gln(Trt)-OH is a glutamine derivative containing amine protecting group Fmoc. Fmoc-Gln(Trt)-OH can be used in solid-phase peptide synthesis .
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1
1 Cited Publications
Cat. No.: HY-W010712
CAS No.: 109425-51-6
Research Areas:  

Others

Fmoc-His(Trt)-OH is a histidine derivative with a trityl (Trt) group protecting the His side chain. Fmoc-His(Trt)-OH also has an Fmoc group protecting the α-NH2 group. Fmoc-His(Trt)-OH can be used in solid-phase peptide synthesis to prevent racemization and byproduct formation. Fmoc-His(Trt)-OH acts as a protected histidine precursor in solid-phase peptide synthesis (SPPS), participating in peptide chain construction through amide bond formation. Fmoc-His(Trt)-OH can be precisely incorporated into the target peptide sequence, ensuring correct peptide chain synthesis and reducing impurity formation. Fmoc-His(Trt)-OH is mainly used in the solid-phase synthesis research of pharmaceutical peptides and bioactive peptides, and is particularly suitable for the preparation of peptide drugs requiring precise control of histidine configuration .
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1
1 Cited Publications
Cat. No.: HY-D1119
CAS No.: 407627-60-5
AF647-NHS ester is an analog of Alexa Fluor 647 (AF647). NHS ester can covalently bind to molecules with amino groups (such as proteins, antibodies, etc.). AF647 is a far-red fluorescent dye with an excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). Storage: Protect from light .
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1
1 Cited Publications
Cat. No.: HY-135233
CAS No.: 76931-93-6
Purity:  99.56%
Synonyms: SATA
N-Succinimidyl S-acetylthioacetate (SATA) is a protein modifying agent. N-Succinimidyl S-acetylthioacetate adds sulfhydryl groups to proteins and other amine-containing molecules in a protected form. N-Succinimidyl-S-acetylthioacetate can thiolate antibodies, thereby promoting efficient attachment of antibodies to other molecules and exerting conjugation activity. N-Succinimidyl-S-acetylthioacetate can be used in immunoassays such as ELISA studies .
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1
1 Cited Publications
Cat. No.: HY-D1244
CAS No.: 1043865-37-7
CO probe 1 (probe 2) is a highly efficient fluorescent CO probe (Ex=493 nm) with an allyl ether reaction site. In the presence of PdCl₂, CO reduces Pd 2+ to Pd 0, triggering a Tsuji-Trost reaction that removes the allyl protecting group, releases fluorescein, and generates a significant fluorescence signal. CO probe 1 has high selectivity, rapid response (fluorescence enhancement of 150 times within 20 minutes), and low cytotoxicity, and can be used for real-time imaging of CO in living cells. CO probe 1 may be used to study pathological mechanisms involving CO signaling regulation, such as inflammation, vascular disease, or cancer .
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Cat. No.: HY-W048739
CAS No.: 312624-65-0
Research Areas:  

Others

Fmoc-α-Me-Leu-OH is a leucine derivative with an Fmoc protecting group, which can be used to synthesize peptides with oxytocin receptor agonist activity .
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Cat. No.: HY-41074
CAS No.: 6638-79-5
N,O-Dimethylhydroxylamine hydrochloride is a biochemical reagent used as a terminal protecting group in oligosaccharide synthesis .
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Cat. No.: HY-W008876
CAS No.: 201531-88-6
Research Areas:  

Others

Fmoc-Pen(Trt)-OH is an amino acid derivative with an Fmoc protecting group that can be used to synthesize the inhibitory cystine knot (ICK) peptide ProTx-II .
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Cat. No.: HY-W047788
CAS No.: 10270-94-7
Research Areas:  

Others

H-Dab(Boc)-OH is an amino acid derivative with a Boc protecting group, which can be used to synthesize methotrexate (MTX) analogs with antitumor and antifolate activities .
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Cat. No.: HY-W013154
CAS No.: 136030-33-6
Research Areas:  

Others

Fmoc-Tic-OH, an Fmoc-protected derivative of Tic, is a solid-phase peptide synthesis monomer. Fmoc-Tic-OH protects the amino group of Tic via a base-labile Fmoc group, allowing conformationally constrained Tic residues to be stepwise coupled to peptide chains, and the Fmoc protecting group can be removed under piperidine conditions. Fmoc-Tic-OH can be used for peptide synthesis and opioid receptor ligand research .
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Cat. No.: HY-W460072
CAS No.: 86013-78-7
Research Areas:  

Others

tert-Butyl 7-hydroxyheptanoate is a linker with a hydroxyl group and a t-butyl ester. The hydroxyl group allows for further derivatization or replacement with many other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
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Cat. No.: HY-W009229
CAS No.: 13726-84-6
Research Areas:  

Others

Boc-Glu (OtBu)-OH is a glutamic acid-derived protected amino acid with its N-terminal amino group protected by tert-butyloxycarbonyl (Boc) and side-chain carboxyl group protected by tert-butyl ester (OtBu), serving as an orthogonally protected building block for polypeptide synthesis. Boc-Glu (OtBu)-OH is applicable to research on the synthesis of peptide compounds .
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Cat. No.: HY-W575291
CAS No.: 1451262-84-2
Synonyms: N-Boc-oct-7-yn-1-amine
Research Areas:  

Others

tert-Butyl oct-7-yn-1-ylcarbamate (N-Boc-oct-7-yn-1-amine) is crosslinker consisting of a propargyl group and a t-Boc protected amine group. The propargyl group reacts with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry reactions. The t-Boc protected amine can be deprotected under mild acidic conditions.
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Cat. No.: HY-W039729
CAS No.: 75178-90-4
Research Areas:  

Others

5-(Boc-amino)-1-pentanol is a linker containing a hydroxyl group and Boc-protected amino group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The Boc group can be deprotected under mild acidic conditions to form the free amine.
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Cat. No.: HY-W077219
CAS No.: 102185-38-6
Synonyms: Boc-Arg(Mtr)-OH
Research Areas:  

Others

Boc-L-Arg(Mtr)-OH (Boc-Arg(Mtr)-OH) is an amino acid derivative with a Boc protecting group, which can be used to synthesize peptides with antithrombotic activity .
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Cat. No.: HY-W259542
CAS No.: 634926-63-9
Research Areas:  

Others

O-Proparagyl-N-Boc-ethanolamine is crosslinker consisting of a propargyl group and a t-Boc protected amine group. The propargyl group reacts with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry reactions. The t-Boc protected amine can be deprotected under mild acidic conditions.
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Cat. No.: HY-PS0011
Target:  

Drug Intermediate

Research Areas:  

Others

Fmoc-Gly-Wang resin is a resin containing a glycine protecting group and can be used for the synthesis of peptides .
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