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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
Silodosin
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "Silodosin" in MCE Product Catalog:
5
5 Cited Publications
Synonyms: KAD 3213; KMD 3213
Target:
Research Areas:
Silodosin (KAD 3213; KMD 3213) is a potent, selective and orally active α1A-adrenergic receptor (α1A-AR) blocker. Silodosin exhibits high affinity for α1A-AR (Ki=0.036 nM), over 162-fold and 50-fold than for α1B-AR and α1D-AR with Ki values of 21 nM and 2.0 nM, respectively. Silodosin is an effective and well-tolerated agent, it can be used for the investigation of LUTS/BPH .
Cat. No.: HY-77037
CAS No.: 239463-85-5
Synonyms: Main Chain of Silodosin
Target:
Research Areas:
(R)-3-(5-(2-Aminopropyl)-7-cyanoindolin-1-yl)propyl benzoate (2R,3R)-2,3-dihydroxysuccinate (Main Chain of Silodosin) is a drug intermediate for synthesis of various active compounds.
Cat. No.: HY-145480
CAS No.: 879292-24-7
Synonyms: Silodosin β-D-glucuronide sodium; KMD-3213G sodium
Target:
Research Areas:
Silodosin Glucuronide (Silodosin β-D-glucuronide; KMD-3213G) sodium is generated in vivo via glucuronidation of the α1A-adrenoceptor antagonist Silodosin (HY-10122). Silodosin Glucuronide sodium is a key biomarker measured simultaneously with the parent drug in human pharmacokinetic/bioequivalence studies of Silodosin formulations .
Cat. No.: HY-158238S
CAS No.: 2851016-14-1
Synonyms: Silodosin β-D-glucuronide-d4; KMD-3213G-d4
Research Areas:
Silodosin Glucuronide-d4 (Silodosin β-D-glucuronide-d4; KMD-3213G-d4) is the deuterated-labeled Silodosin Glucuronide (HY-164132). Silodosin Glucuronide (Silodosin β-D-glucuronide; KMD-3213G) is generated in vivo via glucuronidation of the α1A-adrenoceptor antagonist Silodosin (HY-10122). Silodosin Glucuronide is a key biomarker measured simultaneously with the parent drug in human pharmacokinetic/bioequivalence studies of Silodosin formulations .
Cat. No.: HY-144165S
Cat. No.: HY-Z12431
CAS No.: 1357252-79-9
Synonyms: KMD-3293
Target:
Research Areas:
Silodosin carboxylic acid impurity (KMD-3293) is an inactive silodosin metabolite. Silodosin carboxylic acid impurity is the major metabolite that can be generated via oxidation by alcohol and aldehyde dehydrogenase. Silodosin carboxylic acid impurity can be studied in research for benign prostatic hyperplasia .
Cat. No.: HY-144166S
Cat. No.: HY-10122S
CAS No.: 1426173-86-5
Cat. No.: HY-134632
CAS No.: 175870-21-0
Synonyms: KMD-3241
Target:
Research Areas:
Dehydro silodosin (KMD-3241) is a selective α1A-adrenoceptor antagonist used in the study of benign prostatic hyperplasia .
Cat. No.: HY-10122R
CAS No.: 160970-54-7
Synonyms: KAD 3213 (Standard); KMD 3213 (Standard)
Research Areas:
Silodosin (Standard) is the analytical standard of Silodosin. This product is intended for research and analytical applications. Silodosin (KAD 3213; KMD 3213) is a potent, selective and orally active α1A-adrenergic receptor (α1A-AR) blocker. Silodosin exhibits high affinity for α1A-AR (Ki=0.036 nM), over 162-fold and 50-fold than for α1B-AR and α1D-AR with Ki values of 21 nM and 2.0 nM, respectively. Silodosin is an effective and well-tolerated agent, it can be used for the investigation of LUTS/BPH .
Cat. No.: HY-164132
CAS No.: 879396-70-0
Synonyms: Silodosin β-D-glucuronide; KMD-3213G
Target:
Research Areas:
Silodosin Glucuronide (Silodosin β-D-glucuronide; KMD-3213G) is generated in vivo via glucuronidation of the α1A-adrenoceptor antagonist Silodosin (HY-10122). Silodosin Glucuronide is a key biomarker measured simultaneously with the parent drug in human pharmacokinetic/bioequivalence studies of Silodosin formulations .
Cat. No.: HY-10122A
CAS No.: 160970-64-9
Synonyms: (Rac)-KAD 3213; (Rac)-KMD 3213
Target:
Research Areas:
(Rac)-Silodosin ((Rac)-KAD 3213) is the racemate of Silodosin (HY-10122). Silodosin is a potent, selective and orally active α1A-adrenergic receptor (α1A-AR) blocker .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
