9 Results for "

TFLLRNPNDK-NH2

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "TFLLRNPNDK-NH2" in MCE Product Catalog:

Cat. No.: HY-P5371
CAS No.: 145229-90-9
Target:  

Thrombin

Research Areas:  

Others

TFLLRNPNDK-NH2 is a biological active peptide. (This peptide is a thrombin receptor activating peptide. This PAR-1 agonist peptide reversibly binds to PAR-1 mimicking the 'tethered ligand' that thrombin makes available through proteolytic cleavage of substrate. It is also known to cause increase in liquid and protein permeability much like thrombin.)
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3
3 Cited Publications
Cat. No.: HY-P0226
CAS No.: 197794-83-5
TFLLR-NH2 is a selective PAR1 agonist with an EC50 of 1.9 μM.
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3
3 Cited Publications
Cat. No.: HY-P0226A
CAS No.: 1313730-19-6
Research Areas:  

Others

TFLLR-NH2 (TFA) is a selective PAR1 agonist with an EC50 of 1.9 μM.
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Cat. No.: HY-P2518
CAS No.: 141136-85-8
Protease-Activated Receptor-1, PAR-1 Agonist is a selective proteinase-activated receptor1 (PAR-1) agonist peptide. Protease-Activated Receptor-1, PAR-1 Agonist corresponds to PAR1 tethered ligand and which can selectively mimic theactions of thrombin via this receptor [2].
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Cat. No.: HY-P5360
CAS No.: 244095-36-1
TFLLRN-NH2 is a PAR-1 peptide-selective agonist. TFLLRN-NH2 induces AMPK phosphorylation and attenuates LPS-induced osteoclastogenesis, NFATc1 expression, NF-κB activation, and IκBα degradation. TFLLRN-NH2 stimulates MAPK phosphorylation in hepatocellular carcinoma cells. TFLLRN-NH2 induces concentration-dependent contraction of isolated human renal artery rings, stimulates IL-6 release from human T cells, and also evokes intracellular Ca 2+ mobilization in primary human renal tubular epithelial cells. TFLLRN-NH2 can be used in research related to hepatocellular carcinoma and acute lung injury [2] .
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Cat. No.: HY-P5001
CAS No.: 150242-29-8
Synonyms: iso-SFLLRN
iso-TRAP-6 (iso-SFLLRN) is a PAR-1 agonist that can activate platelets. iso-TRAP-6 is an analog of TRAP-6 (HY-P0078) that refers to the use of isoserine instead of serine as first amino acid .
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Cat. No.: HY-P5359
CAS No.: 141136-84-7
Synonyms: TRAP-6 (2-6)
Research Areas:  

Others

FLLRN is a biological active peptide. (PAR1-specific antagonist peptide)
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Cat. No.: HY-P5373
CAS No.: 237409-87-9
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Ser-parafluoroPhe-Aad-Leu-Arg-Asn-Pro-NH2 is a biological active peptide. (Structure-activity studies of thrombin receptor-tethered ligand SFLLRNP have revealed the importance of the Phe-2-phenyl group in receptor recognition and the replacement of the Phe-2 by para-fluorophenylalanine [(p-F)Phe] was found to enhance its activity)
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Cat. No.: HY-P2518A
Research Areas:  

Cancer

Protease-Activated Receptor-1, PAR-1 Agonist TFA is a selective proteinase-activated receptor1 (PAR-1) agonist peptide. Protease-Activated Receptor-1, PAR-1 Agonist TFA corresponds to PAR1 tethered ligand and which can selectively mimic theactions of thrombin via this receptor [2].
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