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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
ethanol preference
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "ethanol preference" in MCE Product Catalog:
1
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N6-(4-Hydroxybenzyl) adenosine (Para-topolin riboside) is an equilibrative nucleoside transporter 1 (ENT1) inhibitor and a selective agonist of adenosine A2a receptor (A2aR), and also exhibits activity against P2Y12 receptor. N6-(4-Hydroxybenzyl) adenosine reduces ethanol intake and preference, attenuates operant conditioning-induced ethanol place preference, decreases the value of ethanol-related rewards, and inhibits collagen-induced platelet aggregation. N6-(4-Hydroxybenzyl) adenosine can be used in studies related to alcohol use disorder .
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(S)-UFR2709 (hydrochloride) is a competitive nAChR antagonist?and displays higher affinity for α4β2 nAChRs than for α7 nAChRs. (S)-UFR2709 (hydrochloride) decreases anxiety and reduces ethanol consumption and ethanol preference in alcohol-preferring rats. (S)-UFR2709 (hydrochloride) acts as an anxiolytic agent and can be used for the study of nicotine addiction .
Cat. No.: HY-N2086S
CAS No.: 1215721-57-5
Synonyms: Ethyl hexadecanoate-d31
Cat. No.: HY-158051
CAS No.: 1620195-03-0
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CIDD-0072424 selectively inhibits Protein Kinase C-epsilon (PKCε) (Ki=54 nM). CIDD-0072424 reduces ethanol consumption and preference in a dose-dependent manner .
Cat. No.: HY-137231A
CAS No.: 1431628-22-6
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(S)-UFR2709 is a competitive nAChR antagonist and displays higher affinity for α4β2 nAChRs than for α7 nAChRs. (S)-UFR2709 decreases anxiety and reduces ethanol consumption and ethanol preference in alcohol-preferring rats. (S)-UFR2709 acts as an anxiolytic agent and can be used for the study of nicotine addiction .
Cat. No.: HY-122666
CAS No.: 949588-40-3
Synonyms: SCH 900435
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Org 25935 is a potent and selective glycine transporter 1 protein (GlyT1) inhibitor with an IC50 value of 100 nM. Org 25935 can decrease ethanol (EtOH) intake and EtOH preference in rats, whereas water intake is unaffected. Org 25935 can be used for researching alcohol dependence or abuse .
Cat. No.: HY-112074
CAS No.: 31428-61-2
Synonyms: HOE 440
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Tiamenidine (HOE 440) is an orally active α-2 adrenoceptor agonist. Tiamenidine stimulates peripheral α-adrenergic receptors, causing a transient increase in blood pressure, and activates central adrenergic receptors, inhibiting sympathetic nerve activity. Tiamenidine lowers blood pressure in hypertensive rats and inhibits plasma renin activity. Tiamenidine reduces ethanol preference and intake in ethanol-preferring rats. Tiamenidine attenuates Xylazine-induced loss of righting reflex. Tiamenidine can be used in research on hypertension .
Cat. No.: HY-112074A
CAS No.: 51274-83-0
Synonyms: HOE 440 hydrochloride
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Tiamenidine hydrochloride (HOE 440 hydrochloride) is an orally active α-2 adrenoceptor agonist. Tiamenidine hydrochloride stimulates peripheral α-adrenergic receptors, causing a transient increase in blood pressure, and activates central adrenergic receptors, inhibiting sympathetic nerve activity. Tiamenidine hydrochloride lowers blood pressure in hypertensive rats and inhibits plasma renin activity. Tiamenidine hydrochloride reduces ethanol preference and intake in ethanol-preferring rats. Tiamenidine hydrochloride attenuates Xylazine-induced loss of righting reflex. Tiamenidine hydrochloride can be used in research on hypertension .
Cat. No.: HY-105034
CAS No.: 87691-91-6
Synonyms: BMY 13859-1 free base
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Tiospirone is a 5-HT2 receptor antagonist with affinity for D2, 5-HT1a, and 5-HT7, and sigma receptors. Tiospirone decreases consumption of ethanol while increasing food intake of rats. Tiospirone can also reduce the reinforcing properties of Cocaine exhibited in the conditioned place preference paradigm .
Cat. No.: HY-137231
CAS No.: 100609-40-3
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UFR2709 hydrochloride is a blood-brain barrier-permeable, non-selective competitive antagonist of neuronal nicotinic acetylcholine receptors (nAChR). UFR2709 hydrochloride exerts anxiolytic effects in adult zebrafish, reduces alcohol-seeking behavior, ethanol consumption and ethanol preference in rats, increases water intake in rats, and does not alter locomotor/grooming activity or body weight in rats. UFR2709 hydrochloride can be used in research related to anxiety disorders, nicotine addiction, alcoholism and alcohol dependence .
Cat. No.: HY-182601
CAS No.: 1639784-02-3
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MC-100093 is an orally active, blood-brain barrier-permeable GLT-1 expression upregulator . MC-100093 upregulates the expression of GLT-1 and xCT in rats, and alleviates sedative agent-induced GLT-1 downregulation, IL-6 upregulation and motor hyperactivity. MC-100093 upregulates GLT-1 expression and enhances glutamate uptake in astrocyte-neuron co-culture systems. MC-100093 reduces ethanol consumption and preference, and exerts gender-specific antidepressant-like effects . MC-100093 can be used in studies related to sedative agent overdose, mood disorders and alcohol use disorders .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
