26 Results for "

oedema

" in MedChemExpress (MCE) Product Catalog:
Products (26)

26 Results for "oedema" in MCE Product Catalog:

Cat. No.: HY-150069
CAS No.: 2271269-01-1
Purity:  99.16%
Target:  

Bcl-2 Family Apoptosis

Research Areas:  

Metabolic Disease

UBX1325 is an Bcl-xL inhibitor that promotes apoptosis in senescent cells. UBX1325 is a potent anti-aging agent that can be used in studies of age-related eye diseases such as diabetic macular oedema (DME), age-related macular degeneration (AMD) and diabetic retinopathy (DR) .
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Cat. No.: HY-101432
CAS No.: 17969-20-9
Purity:  99.52%
Synonyms: ICI-54450; Acidum fenclozicum; Mialex
Target:  

COX

Research Areas:  

Inflammation/Immunology

Fenclozic acid (ICI-54450) is an orally active anti-inflammatory, analgesic, and antipyretic agent. Fenclozic acid exhibits anti-inflammatory activity in Edadjuvant-induced arthritis and Carrageenin-induced oedema in rats. Fenclozic acid can be used for the research of arthritis .
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Cat. No.: HY-U00153
CAS No.: 2470-73-7
Target:  

Drug Derivative

Research Areas:  

Neurological Disease

Dixyrazine, a phenothiazine derivative, can prevent brain oedema induced by intracarotid injection of protamine sulphate.
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Cat. No.: HY-W050088
CAS No.: 55453-87-7
Synonyms: HP 549
Isoxepac (HP 549) is an orally active non-steroidal anti-inflammatory agent. Isoxepac can inhibit Carrageenan (HY-125474) paw oedema, adjuvant-induced polyarthritis, and prostaglandin synthesis. Isoxepac (200 mg) has an analgesic effect after meniscectomy with a low incidence of side effects. Isoxepac can be used in the research of inflammatory (rheumatoid arthritis) and pain-related diseases .
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Cat. No.: HY-B1254
CAS No.: 5588-16-9
Synonyms: Althiazide
Target:  

Others

Research Areas:  

Cardiovascular Disease

Altizide (Althiazide) is an orally active diuretic. Altizide can be used in studies of oedema and hypertension .
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Cat. No.: HY-123179
CAS No.: 7195-27-9
Purity:  ≥99.0%
Target:  

Carbonic Anhydrase

Research Areas:  

Cardiovascular Disease

Mefruside is an orally active diuretic and has a mild hypotensive effect. Mefruside inhibits the synthesis of urea in an isolated rat liver perfusion model. Mefruside can be used in studies of oedema and hypertension .
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Cat. No.: HY-P5875A
P4pal10 TFA is the TFA salt form of P4pal10 (HY-P5875). P4pal10 TFA is an antagonist for protease-activated receptor 4 (PAR4). P4pal10 TFA inhibits the platelet aggregation, inhibits tissue factor (TF)-induced thrombin generation, and exhibits anticoagulant and antithrombotic activities. P4pal10 TFA reduces the oedema and the granulocyte infiltration induced by Carrageenan (HY-125474). P4pal10 TFA ameliorates the injury in rats myocardial ischemia/reperfusion (I/R) models .
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Cat. No.: HY-N2196
CAS No.: 23044-80-6
Ajugasterone C is an ecdysteroid isolated from Leuzea carthamoides. Ajugasterone C shows significant inhibitory effect at 100 mg/kg dose on rat paw oedema development due to Carrageenan-induced inflammation in Sprague Dawley rats .
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Cat. No.: HY-404056
CAS No.: 2151021-59-7
(R)-AZ8838 is a competitive PAR2 antagonist with a pKi of  5.2 for human PAR2. (R)-AZ8838 exert anti-inflammatory effects in a rat model of PAR2 agonist-induced paw oedema .
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Cat. No.: HY-P991415
Synonyms: AM712

Target:  

VEGFR Tie

Research Areas:  

Others

ASKG-712 (AM712) is a recombinant anti-VEGF humanized monoclonal antibody and Ang-2 antagonist peptide fusion protein. ASKG-712 can be used in Wet age-related macular degeneration and Diabetic macular oedema research .
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Cat. No.: HY-105215
CAS No.: 138449-07-7
Target:  

Neurokinin Receptor

Research Areas:  

Inflammation/Immunology

FK888 is a potent, selective, and high affinity dipeptide NK1 receptor antagonist. FK888 displaces [3H]-SP binding with a Ki value of 0.69 nM and 0.45 microM. FK888 also inhibits SP-induced airway oedema in guinea-pig after both intravenous and oral administration .
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Cat. No.: HY-W995241
CAS No.: 213481-12-0
Target:  

COX NF-κB

Research Areas:  

Inflammation/Immunology

BPD is a COX-2 and TAK1-NF-κB inhibitor, with an IC50 of 18.5 μM for COX-2. BPD inhibits the expression of iNOS, TNF-α, IL-6 and IL-1β at the transcriptional level. BPD has anti-inflammatory activity. BPD can inhibit Carrageenan-induced paw oedema and LPS-induced septic death .
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Cat. No.: HY-W050088S
CAS No.: 2012598-71-7
Synonyms: HP 549-d6
Isoxepac-d6 (HP 549-d6) is the deuterium labeled Isoxepac (HY-W050088). Isoxepac (HP 549) is an orally active non-steroidal anti-inflammatory agent. Isoxepac can inhibit Carrageenan (HY-125474) paw oedema, adjuvant-induced polyarthritis, and prostaglandin synthesis. Isoxepac (200 mg) has an analgesic effect after meniscectomy with a low incidence of side effects. Isoxepac can be used in the research of inflammatory (rheumatoid arthritis) and pain-related diseases .
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Cat. No.: HY-P991416

Target:  

VEGFR

Research Areas:  

Others

BAT5906 is a human monoclonal antibody (mAb) targeting VEGFA. BAT5906 can be used in Wet age-related macular degeneration and Diabetic macular oedema research .
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Cat. No.: HY-U00153R
CAS No.: 2470-73-7
Research Areas:  

Neurological Disease

Dixyrazine (Standard) is the analytical standard of Dixyrazine. This product is intended for research and analytical applications. Dixyrazine, a phenothiazine derivative, can prevent brain oedema induced by intracarotid injection of protamine sulphate.
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Cat. No.: HY-P991385

Target:  

Tie

UBX2050 is a human monoclonal antibody (mAb) targeting TIE2. UBX2050 can be used in Age-related macular degeneration, Diabetic macular oedema and Diabetic retinopathy research .
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Cat. No.: HY-N10226
CAS No.: 71950-67-9
Thielavin B is an inhibitor of prostaglandin biosynthesis produced by Thielavia terricola. Thielavin B effectively influences the prostaglandin E2 synthesis from the endoperoxide. Thielavin B is significantly effective on carrageenan-induced oedema of rats when administered intravenously .
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Cat. No.: HY-14886
CAS No.: 1157852-02-2
Synonyms: MEN16132 free base
Fasitibant chloride (MEN16132 free base) is a potent and selective nonpeptide bradykinin B2 receptor (B2R) antagonist. Fasitibant chloride reduces joint pain and diminishes joint oedema in Carrageenan-induced arthritis rat model .
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Cat. No.: HY-133173
CAS No.: 130610-93-4
Synonyms: RU51599
Niravoline (RU51599) is an arginine vasopressin (AVP) release inhibitor and a selective kappa opioid receptor agonist. Niravoline has a pure water diuresis effect without associated electrolyte excretion. Niravoline can reduce brain oedema following transient forebrain ischaemia in rats .
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Cat. No.: HY-148925
CAS No.: 638-96-0
α-Amyrenone is a triterpenoid that occurs naturally in very low concentrations in several oleoresins from Brazilian Amazon species of Protium (Burseraceae). The mixture of α and β-amyrenone inhibits α-glucosidase, and can reduce mechanical hypersensitivity and paw-oedema induced by carrageenan .
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