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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
36 Results for "
PAO
" in MedChemExpress (MCE) Product Catalog:
Products (36)
36 Results for "PAO" in MCE Product Catalog:
3
3 Cited Publications
Cat. No.: HY-Q36392
CAS No.: 326923-09-5
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JNJ-9350, a chemical probe, is an inhibitor of spermine oxidase (SMOX) with an IC50 value of 0.01 μM. JNJ-9350 also inhibits polyamine oxidase (PAO) with an IC50 value of 0.79 μM. JNJ-9350 can be used for the research of cancer .
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2 Cited Publications
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MDL 72527 is a potent polyamine oxidase (PAO) inhibitor. MDL 72527 shows a lysosomotropic effect. MDL 72527 shows neuroprotective effects .
2
2 Cited Publications
Synonyms: Oxophenylarsine; PhAsO; Arsenosobenzene
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Phenylarsine oxide (PAO), an inhibitor of endocytosis, inhibits PTPε with an IC50 of 18 μM. Phenylarsine oxide (PAO) inhibits oxygen consumption and decreases cellular ATP content overlap with those used to inhibit protein internalization .
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Cat. No.: HY-N2594
CAS No.: 1357910-26-9
Category:
Infection Plant Simple Phenylpropanols Phenols Polyphenols Phenylpropanoids Oleaceae Extract Disease Research Fields Forsythia suspensa (Thunb.) Vahl Extract
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Cat. No.: HY-W002016
CAS No.: 253-52-1
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Cardiovascular Disease Infection Metabolic Disease Inflammation/Immunology Cancer
Phthalazine is a chemical scaffold. Phthalazine derivatives act as VEGFR-2 inhibitors, PARP-1 inhibitors, and anticancer agents. The complex of phthalazine with silver exhibits broad-spectrum antibacterial and antifungal activities against Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa PAO1, and Candida albicans. Phthalazine derivatives possess potent vasodilatory activity. Phthalazine can be used in research related to colon adenocarcinoma, breast cancer, hypertension, diabetes, and microbial infections .
Cat. No.: HY-126369
CAS No.: 105613-48-7
Synonyms: HM-PAO
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Exametazime (HM-PAO) is a lipophilic agent used for the preparation of brain imaging radiopharmaceuticals. 99Tcm-Exametazime is an effective in vitro leukocyte labeling agent .
Cat. No.: HY-W700715
CAS No.: 1215622-76-6
3-Hydroxyoctanoic acid-d12 is the deuterated-labeled 3-Hydroxyoctanoic acid (HY-113058). 3-Hydroxyoctanoic acid is a medium-chain β-hydroxy fatty acid that possesses antibacterial, antifungal, and quorum-sensing regulatory activities. 3-Hydroxyoctanoic acid is an endogenous agonist of the human HCAR3 receptor, decreases intracellular cAMP, reduces IL-1beta secretion, increases IL-10 secretion, and decreases ROS production in macrophages. 3-Hydroxyoctanoic acid inhibits quorum-sensing-regulated pyocyanin production in Pseudomonas aeruginosa PAO1 and inhibits the yeast-to-hypha transition in Candida albicans. 3-Hydroxyoctanoic acid is used in research related to metabolism, bacterial infections, and fungal infections .
Cat. No.: HY-D1267
CAS No.: 1613402-20-2
PAO-Nap is the modified PAO attached a naphthalimide fluorophore using aminocaproic acid as a linker. PAO induces oxidative stress-mediated apoptosis in HL-60 cells by selectively targeting thioredoxin reductase .
Cat. No.: HY-D1268
CAS No.: 851461-65-9
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ML318 is a biaryl nitrile inhibitor of PvdQ acylase with an IC50 of 20 nM by binding in the acyl-binding site. ML318 inhibits P. aeruginosa (PAO1) with an IC50 of 19 μM. ML318 prevents pyoverdine production and limits the growth of P. aeruginosa under iron-limiting conditions .
Cat. No.: HY-113056AR
CAS No.: 34450-16-3
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Cat. No.: HY-RS10024
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PAOX Human Pre-designed siRNA Set A contains three designed siRNAs for PAOX gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-163481
CAS No.: 3033920-95-2
Antibiofilm agent-6 (Compound 26c) is a quorum sensing inhibitor with strong antibiofilm effects that can inhibit the fluorescence intensity of PAO1-lasB-gfp and PAO1-pqsA-gfp in a concentration-dependent manner. Antibiofilm agent-6 can inhibit the production of pyocyanin and rhamnolipid. Antibiofilm agent-6 aids helps ciprofloxacin (HY-B0356) effectively eliminate the living bacteria in a mouse model infected with P. aeruginosa PAO1 .
Cat. No.: HY-RS18371
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Smox Mouse Pre-designed siRNA Set A contains three designed siRNAs for Smox gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-146304
CAS No.: 2415981-79-0
YXL-13 is a potent Pseudomonas aeruginosa (PAO1) inhibitor with an IC50 value of 3.686 μM. YXL-13 can inhibit virulence factors and biofilm formation of PAO1. YXL-13 reduces the pathogenicity and agent resistance of PAO1 by inhibition of the quorum sensing (QS) system. YXL-13 can be used for researching anti-bacteria .
Cat. No.: HY-RS13446
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SMOX Human Pre-designed siRNA Set A contains three designed siRNAs for SMOX gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-W680647
CAS No.: 99207-33-7
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MDL 72527 free base is a potent polyamine oxidase (PAO) inhibitor. MDL 72527 free base shows a lysosomotropic effect. MDL 72527 shows neuroprotective effects .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
