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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
23 Results for "
enzyme cleavage activity
" in MedChemExpress (MCE) Product Catalog:
Products (23)
23 Results for "enzyme cleavage activity" in MCE Product Catalog:
51
51 Publications Verification
Cat. No.: HY-108882C
CAS No.: 9003-98-9
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DNase I is an enzyme that degrades DNA. DNase I is mainly produced by digestive system organs, such as the pancreas and parotid gland. Three types of DNase I are known in mammals: pancreatic type, parotid type, and pancreatico-parotid type. DNase I plays a key role in the cleavage of extracellular DNA, and is critical for limiting inflammatory responses and maintaining homeostasis. DNase I is responsible for digesting extracellular nucleoproteins, which may be essential for preventing autoimmune reactions. Decreased DNase I activity may be associated with the occurrence and development of systemic lupus erythematosus (SLE). DNase I (filtered) is filtered through a 0.22 μM membrane and is not tested for pyrogenicity .
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51 Publications Verification
Cat. No.: HY-108882B
CAS No.: 9003-98-9
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DNase I is an enzyme that degrades DNA. DNase I is mainly produced by digestive system organs, such as the pancreas and parotid gland. Three types of DNase I are known in mammals: pancreatic type, parotid type, and pancreatico-parotid type. DNase I plays a key role in the cleavage of extracellular DNA, and is critical for limiting inflammatory responses and maintaining homeostasis. DNase I is responsible for digesting extracellular nucleoproteins, which may be essential for preventing autoimmune responses. Decreased DNase I activity may be associated with the onset and progression of systemic lupus erythematosus (SLE). DNase I (RNase & Protease free) is a molecular biology-grade DNase I purified by chromatography to remove RNase and protease .
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1 Cited Publications
Cat. No.: HY-P3722
CAS No.: 192723-42-5
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1 Cited Publications
Cat. No.: HY-P3722A
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Aldolase, Rabbit muscle (Fructose-diphosphate aldolase) is a glycolytic enzyme and glucose availability sensor. Aldolase, Rabbit muscle catalyzes the reversible carbon-carbon cleavage of fructose-1,6-bisphosphate to produce dihydroxyacetone phosphate and glyceraldehyde 3-phosphate. Aldolase, Rabbit muscle is an essential component for v-ATPase activity. Aldolase, Rabbit muscle participates in processes such as gluconeogenesis, the Calvin cycle and glycolysis .
Cat. No.: HY-P4344
CAS No.: 1926163-52-1
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Cat. No.: HY-W748591
CAS No.: 76735-57-4
Cat. No.: HY-W009454
CAS No.: 6217-68-1
Synonyms: 4-Nitopheyl Sulfate potassium
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Potassium p-nitrophenyl sulfate (4-Nitophenyl Sulfate potassium) serves as a chromogenic substrate for arylsulfatases. Potassium p-nitrophenyl sulfate releases nitrophenol under the cleavage action of arylsulfatases, and the activity of arylsulfatases can be quantitatively determined via colorimetric detection at 400 nm. Potassium p-nitrophenyl sulfate is commonly used in enzyme inhibition assays and metabolite analog-related studies .
Cat. No.: HY-N0499A
CAS No.: 13306-05-3
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Cat. No.: HY-169491
CAS No.: 1224691-12-6
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Pantothenate-AMC is a fluorogenic substrate used for detecting the enzymatic activity of vanin-1, an enzyme involved in the recycling of L-pantothenic acid. Upon enzymatic cleavage by vanin-1, 7-amino-7-methylcoumarin (AMC) is released, and its fluorescence can be used to quantify vanin-1 activity. The excitation/emission maxima of AMC are 340-360 nm and 440-460 nm, respectively .
Cat. No.: HY-146307
CAS No.: 2445565-58-0
TrxR-IN-3 is a thioredoxin reductase (TrxR) inhibitor with an IC50 of 0.12 µM in MDA-MB-231 cells. TrxR-IN-3 inhibits TrxR enzyme activity and suppresses TrxR protein expression. TrxR-IN-3 induces reactive oxygen species (ROS) accumulation, apoptosis, and autophagy. TrxR-IN-3 modulates apoptosis-related proteins by decreasing anti-apoptotic protein levels and increasing caspase cleavage. TrxR-IN-3 modulates autophagy-related proteins by increasing autophagy markers and reducing autophagy substrate proteins. TrxR-IN-3 can be used for breast cancer research .
Cat. No.: HY-149373
CAS No.: 76996-28-6
Cat. No.: HY-P5510
CAS No.: 188530-20-3
Synonyms: HCV NS3 protease substrate
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Cat. No.: HY-W748591R
CAS No.: 76735-57-4
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Cat. No.: HY-P12222
Mca-AQTLTL-Dpa-RSSSQ-NH2 is a fluorescent substrate peptide for TNF-α converting enzyme (TACE), with its peptide sequence spanning the TACE cleavage site of tmTNF. In its intact state, the fluorescence of Mca-AQTLTL-Dpa-RSSSQ-NH2 is quenched; upon cleavage by TACE, a fluorescent signal is released, thereby reflecting TACE enzymatic activity. Mca-AQTLTL-Dpa-RSSSQ-NH2 can be used for studies related to TACE activity and TACE inhibition .
Cat. No.: HY-E71248
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α-Rhamnosidase 78A, Streptomyces avermitilis (EC 3.2.1.40) is a thermostable Alpha-L-Rhamnosidase (Naringinase, RhamA) that catalyzes the cleavage of the bond between terminal L (+)-rhamnose and the aglycone of rhamnose-containing glycosides. The enzyme is very active on naringin but has also substantial activity with hesperidin as substrate.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
