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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
thermal oxidation
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "thermal oxidation" in MCE Product Catalog:
11
11 Publications Verification
Cat. No.: HY-18732A
CAS No.: 53308-83-1
Synonyms: Tilarginine acetate; Methylarginine acetate
Category:
Cardiovascular Disease Natural Products Endogenous metabolite Disease Research Fields Cancer
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11
11 Publications Verification
Cat. No.: HY-18732
CAS No.: 17035-90-4
Synonyms: Tilarginine; Methylarginine
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Research Areas:
L-NMMA (Tilarginine) is a non-selective and competitive inhibitor of nitric oxide synthase. L-NMMA inhibits three subtypes, namely nNOS, eNOS, and iNOS, and reduces NO production . L-NMMA alleviates mechanical allodynia, thermal hyperalgesia, and choroidal fibrosis. L-NMMA is applicable to research related to nociception, bone cancer pain, and myopia .
Cat. No.: HY-D1005A8
CAS No.: 9003-11-6
Synonyms: PEG-PPG-PEG, 2000 (Average)
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Research Areas:
Sodium Tartrate (E335ii) is an approved food additive that functions as both a pH regulator and an emulsifier. Sodium Tartrate effectively inhibits hydrolysis, thermal oxidation, polymerization and coloration of vegetable oil during high-temperature heating, exhibiting significant antioxidant activity. The DL-tartaric acid component of Sodium Tartrate has an absorption rate of up to 90% in brown rats, while the absorption rate of related tartaric acid in humans is only 20% .
Cat. No.: HY-W087905
CAS No.: 1889-67-4
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Research Areas:
2,3-Dimethyl-2,3-diphenylbutane is a minor product formed during the thermal decomposition of dicumyl peroxide (DCP) in cumene, generated through radical coupling reactions. As an initiator capable of producing free radicals, 2,3-dimethyl-2,3-diphenylbutane promotes cross-linking or decomposition processes via initiating free radical reactions in fields such as polymer polymerization (e.g., modification of polyphenylene oxide processing), organic synthesis (e.g., DCP decomposition reactions), and coal processing (e.g., oxidation stabilization of coal tar pitch), thereby enhancing material properties or reaction efficiency .
Cat. No.: HY-N4017
CAS No.: 34427-61-7
Synonyms: 7α-Hydroxysitosterol
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Cat. No.: HY-W009641
CAS No.: 24463-15-8
Synonyms: PyM; 1-HMP
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Research Areas:
1-Pyrenemethanol is an organic compound that can be used to prepare graphene films with excellent thermal conductivity, flexibility and mechanical properties. 1-Pyrenemethanol binds to graphene oxide sheets through hydrogen bonds and π-π interactions to form GO-PyM films, increasing the dispersion and stability of the material .
Cat. No.: HY-125209A
CAS No.: 2253744-57-7
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TH5427 hydrochloride is a NUDT5 inhibitor with a human target IC50 of 29 nM, ~690-fold selectivity over MTH1 in vitro, and selective functional inhibition over other NUDIX hydrolases including NUDT9 .TH5427 hydrochloride binds to the active site of NUDT5, blocking enzymatic activity related to ADP-ribose metabolism and PAR-derived ATP synthesis .TH5427 hydrochloride blocks progestin-dependent nuclear ATP synthesis, impairs progestin-induced chromatin remodeling, inhibits histone H1 displacement, disrupts progestin-dependent gene regulation, and abrogates progestin-dependent proliferation in breast cancer cells .TH5427 hydrochloride functions as a versatile probe to study nuclear ATP dynamics and ADP-ribose-related metabolism in cells .TH5427 hydrochloride engages NUDT5 at physiological temperatures, as demonstrated by Drug Affinity Responsive Target Stability (DARTS) assay .TH5427 hydrochloride stabilizes NUDT5 against thermal denaturation in cell lysates and intact cells, as shown by cellular thermal shift assay (CETSA) .TH5427 hydrochloride functionally inhibits NUDT5 activity, leading to downstream effects on oxidative DNA damage and DNA replication in triple-negative breast cancer (TNBC) cells .TH5427 hydrochloride suppresses proliferation of TNBC cells without inducing cell death or apoptosis, slows DNA replication in TNBC cells, promotes accumulation of oxidative DNA lesions, and triggers DNA damage response in TNBC cells .TH5427 hydrochloride suppresses growth of TNBC cells in vitro, inhibits growth of TNBC xenograft tumors in nude mice in vivo, and shows greater potency against TNBC cell lines compared to ER-positive and normal-like breast cell lines .TH5427 hydrochloride can be used for the research of breast cancer and triple-negative breast cancer .
Cat. No.: HY-W004606
CAS No.: 6267-02-3
Synonyms: DM-AD
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Research Areas:
9,9-Dimethyl-9,10-dihydroacridine (DM-AD) is an electron-donating group with hole transport mobility, which serves as a building block for the synthesis of organic semiconductors and light-emitting emitters. 9,9-Dimethyl-9,10-dihydroacridine can form donor-acceptor-donor type thermally activated delayed fluorescence emitters. 9,9-Dimethyl-9,10-dihydroacridine undergoes oxidation to form radical cations, which further participate in dimerization or oligomerization reactions .
Cat. No.: HY-N6875
CAS No.: 96382-90-0
Category:
Metabolic Disease Other Families Extract Plant Iridoids Terpenoids Burseraceae Extract Phenols Polyphenols Disease Research Fields Canarium album (Lour.) Rauesch. Extract
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Cat. No.: HY-18732C
CAS No.: 156706-47-7
Synonyms: Tilarginine hydrochloride; Methylarginine hydrochloride
Target:
Research Areas:
L-NMMA (Tilarginine) hydrochloride is a non-selective and competitive inhibitor of nitric oxide synthase. L-NMMA hydrochloride inhibits three subtypes, namely nNOS, eNOS, and iNOS, and reduces NO production . L-NMMA hydrochloride alleviates mechanical allodynia, thermal hyperalgesia, and choroidal fibrosis. L-NMMA hydrochloride is applicable to research related to nociception, bone cancer pain, and myopia .
Cat. No.: HY-18732B
CAS No.: 209913-88-2
Synonyms: Methylarginine citrate; Tilarginine citrate
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Research Areas:
L-NMMA (Tilarginine) citrate is a non-selective and competitive inhibitor of nitric oxide synthase. L-NMMA citrate inhibits three subtypes, namely nNOS, eNOS, and iNOS, and reduces NO production . L-NMMA citrate alleviates mechanical allodynia, thermal hyperalgesia, and choroidal fibrosis. L-NMMA citrate is applicable to research related to nociception, bone cancer pain, and myopia .
Cat. No.: HY-W142432R
CAS No.: 2058-94-8
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Research Areas:
Perfluoroundecanoic acid (Standard) is the analytical standard of Perfluoroundecanoic acid. This product is intended for research and analytical applications. Perfluoroundecanoic acid is an orally active inducer of oxidative stress and DNA damage. Perfluoroundecanoic acid exhibits genotoxicity and reproductive toxicity in swiss mice. Perfluoroundecanoic acid is utilized as a processing aid in the manufacture of fluoropolymer for its thermal and pressure stability, and properties of having both water-repellent and oil-repellent groups and hydrophilic groups on the same molecule .
Cat. No.: HY-18732AR
CAS No.: 53308-83-1
Synonyms: Tilarginine acetate (Standard); Methylarginine acetate (Standard)
Category:
Target:
Cat. No.: HY-133077
CAS No.: 34812-73-2
Synonyms: DEC N-oxide
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Research Areas:
Diethylcarbamazine N-oxide (DEC N-oxide) is the N-oxide metabolite of Diethylcarbamazine (HY-12642A). Diethylcarbamazine N-oxide is stable to extraction in alkalinized urine but with low efficiency, and can be converted to Diethylcarbamazine upon thermal decomposition or reduction by sulfur dioxide. Diethylcarbamazine N-oxide can be used for the study of Diethylcarbamazine metabolism .
Cat. No.: HY-W540405
CAS No.: 3404-72-6
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Cat. No.: HY-184634
OA Coated Fe3O4 Nanoparticles (Oleic acid-modified iron(III) oxide nanoparticles) were prepared using a high-temperature pyrolysis method. Oleic acid was added as a surfactant to a solution containing an iron precursor. Oleic acid not only helps control the growth of nanoparticles but also forms a stable coating on the particle surface. The solution containing the iron precursor and oleic acid was heated to a high temperature, typically around 300°C, to promote the thermal decomposition of the iron precursor. At high temperatures, the iron precursor decomposes to produce iron atoms, which aggregate to form magnetic nanoparticles. During pyrolysis, the iron nanoparticles react with oxygen in the air to form iron(III) oxide (Fe3O4).
Cat. No.: HY-D3111
CAS No.: 1240465-12-6
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DBHA is a long-wavelength polarity-sensitive fluorescent probe based on Nile Red. Under the catalysis of Pd (OAc)2/TPPTS, DBHA site-selectively labels protein tyrosine residues via a π-allyl palladium complex intermediate. Utilizing the property that its maximum emission wavelength blue-shifts with decreasing local polarity (650 nm in aqueous solution → 584-608 nm in hydrophobic domains), it detects changes in local polarity and conformation of protein tyrosine domains under acid/thermal denaturation conditions. DBHA can be used in studies related to SOD1-associated oxidative stress neurodegenerative diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
